Structural maintenance of chromosomes (SMC) complexes are ubiquitous genome
regulators with a wide range of functions. Among the three types of SMC complexes in …

The hepatitis B virus (HBV) counts as a major global health problem, as it presents a
significant causative factor for liver-related morbidity and mortality. The development of …

Background Accumulated evidence highlights the significance of the crosstalk between
epigenetic and epitranscriptomic mechanisms, notably 5-methylcytosine (5mC) and N6 …

Targeted protein degradation (TPD) represents a revolutionary therapeutic strategy in
disease management, providing a stark contrast to traditional therapeutic approaches like …

The evidence for chronic hepatitis B virus (HBV) infection and hepatocellular carcinoma
(HCC) occurrence is well established. The hepatocyte epithelium carcinogenesis caused by …

Hepatitis B virus (HBV) infection remains a major public health concern worldwide, with
approximately 296 million individuals chronically infected. The HBV-encoded X protein …

Hepatitis B virus infections have always been associated with high levels of mortality. In
2019, hepatitis B virus (HBV)-related diseases resulted in approximately 555,000 deaths …

With 296 million chronically infected individuals worldwide, hepatitis B virus (HBV) causes a
major health burden. The major challenge to cure HBV infection lies in the fact that the …

Hepatitis B, a global health concern caused by the hepatitis B virus (HBV), infects nearly 2
billion individuals worldwide, as reported by the World Health Organization (WHO). HBV, a …

High-level folding of chromatin is a key determinant of the shape and functional state of
chromosomes. During cell division, structural maintenance of chromosome (SMC) …