MYC, a major oncogenic transcription factor, regulates target genes involved in various
pathways such as cell proliferation, metabolism and immune evasion, playing a critical role …

Nuclear receptors (NRs) have historically been at the forefront of cancer research, where
they are known to act as critical regulators of disease. They also serve as biomarkers for …

Abstract Nuclear receptor coactivator 2 (Ncoa2) is a member of the Ncoa family of
coactivators, and we previously showed that Ncoa2 regulates the differentiation of induced …

T cell activation stimulates substantially increased protein synthesis activity to accumulate
sufficient biomass for cell proliferation. The protein synthesis is fueled by the amino acids …

Steroid nuclear receptor coactivator 2 (SRC2) is a member of a family of transcription
coactivators. While SRC1 inhibits the differentiation of regulatory T cells (Tregs) critical for …

Background: Mitophagy has been found to play a significant part in the cancer process in a
growing number of studies in recent years. However, there is still a lack of study on …

The Hedgehog (Hh) pathway plays diverse roles in cellular processes by activating the
transcription factor Cubitus interruptus (Ci). Abnormal regulation of this pathway has been …

Abstract Dickkopf‐related protein 4 (DKK4) is a member of the dickkopf family and an
inhibitor of the Wnt/β‐catenin signalling pathway. This review surveyed the single nucleotide …

Prion-like behaviour is attracting much attention due to the growing evidences that amyloid-
like self-assembly may reach beyond neurodegeneration and be a conserved functional …

Large-scale genome sequencing studies have identified a wealth of mutations in human
tumors and have dramatically advanced the field of cancer genetics. However, the functional …