Pancreatic cancer (PC) is one of the deadliest cancers associated with poor prognosis. The
lack of reliable means of early cancer detection contributes to this disease's dismal …

ABSTRACT C-Myc overexpression is a common finding in pancreatic cancer and predicts
the aggressive behavior of cancer cells. It binds to the promoter of different genes, thereby …

BACKGROUND Pancreatic cancer, as the one of most fatal malignancies, remains a critical
issue in the global burden of disease. AIM To estimate trends in pancreatic cancer incidence …

Abstract Tumor-associated macrophages (TAMs), as a major and essential component of
tumor microenvironment (TME), play a critical role in orchestrating pancreatic cancer (PaC) …

Type 1 diabetes and type 2 diabetes have high rates of associated exocrine pancreatic
insufficiency (EPI). This review evaluated the current evidence on prevalence and treatment …

Pancreatic cancer is a deadly disease with limited diagnostic and treatment options. Not all
populations are affected equally, as disparities exist in pancreatic cancer prevalence …

Background: Pancreatic cancer (PC) is a highly fatal malignancy with a global overall 5-year
survival of under 10%. Screening of PC is not recommended outside of clinical trials …

Abstract Lysine (K)-specific demethylase 6A (KDM6A) is a frequently mutated tumor
suppressor gene in pancreatic ductal adenocarcinoma (PDAC). However, the impact of …

Fluorouracil (5-FU) is a chemotherapeutic drug widely used to treat patients with solid
tumours, such as colorectal and pancreatic cancers. Colorectal cancer (CRC) is the second …

Pancreatic cystic lesions are an increasingly common clinical finding. They represent a
heterogeneous group of lesions that include two of the three known precursors of pancreatic …