Dolutegravir–a review of the pharmacology, efficacy, and safety in the treatment of HIV

CE Kandel, SL Walmsley - Drug design, development and therapy, 2015 - Taylor & Francis
Dolutegravir is the newest integrase strand transfer inhibitor to be approved for the treatment
of human immunodeficiency virus (HIV) infection. Dolutegravir is equivalent or superior to …

A clinical review of HIV integrase strand transfer inhibitors (INSTIs) for the prevention and treatment of HIV-1 infection

AV Zhao, RD Crutchley, RC Guduru, K Ton, T Lam… - Retrovirology, 2022 - Springer
Integrase strand transfer inhibitors (INSTIs) have improved the treatment of human
immunodeficiency virus (HIV). There are currently four approved for use in treatment-naïve …

The relationship of smoking and unhealthy alcohol use to the HIV care continuum among people with HIV in an integrated health care system

DD Satre, T Levine-Hall, SA Sterling… - Drug and alcohol …, 2021 - Elsevier
Introduction Smoking tobacco and unhealthy alcohol use may negatively influence HIV care
continuum outcomes but have not been examined in combination. Methods Participants …

Real-world adherence and persistence for newly-prescribed HIV treatment: single versus multiple tablet regimen comparison among US medicaid beneficiaries

J Cohen, A Beaubrun, R Bashyal, A Huang, J Li… - AIDS research and …, 2020 - Springer
Background Once-daily, single-tablet regimens (STRs) have been associated with improved
patient outcomes compared to multi-tablet regimens (MTRs). This study evaluated real world …

Antiretroviral treatment gaps and adherence among people with HIV in the US Medicare program

P Li, G Prajapati, Z Geng, VP Ladage, JM Arduino… - AIDS and Behavior, 2024 - Springer
Approximately one-quarter of people with HIV (PWH) in the US receive coverage through
the Medicare program; however, no prior real-world study has examined antiretroviral …

Trends in ART prescription and viral suppression among HIV-positive young adults in care in the United States, 2009–2013

L Beer, CL Mattson, H Bradley… - JAIDS Journal of …, 2017 - journals.lww.com
Background: Only 13% of HIV-positive young adults are estimated to be virally suppressed
and, even among those receiving medical care, HIV-positive young adults are less likely …

Evaluating the role of atazanavir/cobicistat and darunavir/cobicistat fixed-dose combinations for the treatment of HIV-1 infection

RD Crutchley, RC Guduru… - HIV/AIDS-Research and …, 2016 - Taylor & Francis
Atazanavir/cobicistat (ATV/c) and darunavir/cobicistat (DRV/c) are newly approved once
daily fixed-dose protease inhibitor combinations for the treatment of HIV-1 infection. Studies …

Ten-year trends in antiretroviral therapy persistence among US Medicaid beneficiaries

B Youn, TI Shireman, Y Lee, O Galárraga, AI Rana… - Aids, 2017 - journals.lww.com
Objective: Whether the rate of HIV antiretroviral therapy (ART) persistence has improved
over time in the United States is unknown. We examined ART persistence trends between …

Effect of single tablet regimen on prescription trends for treatment-naïve patients with HIV/AIDS in Korea

KS Oh, GH Seo, HK Choi, E Han - Scientific reports, 2022 - nature.com
Single-tablet regimens (STRs) should be considered for patients with HIV/AIDS to increase
medication compliance and improve clinical outcomes. This study compared variations in …

Non‐adherence and non‐persistence with antiretroviral treatment in Belgium: A real‐world evaluation using a pharmacy database, 2018–2021

D Ilboudo, P Mbouche, A Sommet… - … and drug safety, 2024 - Wiley Online Library
Purpose To evaluate the real‐world rates of non‐adherence and non‐persistence to
antiretroviral therapy (ART) among treatment‐naïve adult patients with HIV after a 12‐month …