The success of cancer immunotherapy relies on the knowledge of the tumor
microenvironment and the immune evasion mechanisms in which the tumor, stroma, and …

Cancer is one of the leading causes of death in the United States along with heart disease.
The hallmark of cancer treatment has been conventional chemotherapy. Chemotherapeutic …

Recent findings have uncovered novel fascinating aspects of the biology of neutrophils,
which ultimately attribute to these cells a broader role in inflammation and immunity. One …

Purpose: mAbs are used to treat solid and hematologic malignancies and work in part
through Fc receptors (FcRs) on natural killer cells (NK). However, FcR-mediated functions of …

Target-based drug discovery is the dominant paradigm of drug discovery; however, a
comprehensive evaluation of its real-world efficiency is lacking. Here, a manual systematic …

First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
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Background Cancer immunotherapy can be potentiated by conditioning regimens such as
cyclophosphamide, which reduces the level of regulatory T cells (tregs). However, myeloid …

Around 15 years ago, imatinib mesylate (Gleevec® or Glivec®, Novartis, Switzerland)
became the very first'targeted'anticancer drug to be clinically approved. This drug constitutes …

First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
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First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
52478098&utm_source= google_patent&utm_medium= platform_link&utm_campaign …