Fragment Screening and Fast Micromolar Detection on a Benchtop NMR Spectrometer Boosted by Photoinduced Hyperpolarization
GR Stadler, TF Segawa, M Bütikofer… - Angewandte Chemie …, 2023 - Wiley Online Library
Fragment‐based drug design is a well‐established strategy for rational drug design, with
nuclear magnetic resonance (NMR) on high‐field spectrometers as the method of reference …
nuclear magnetic resonance (NMR) on high‐field spectrometers as the method of reference …
Leveraging ligand affinity and properties: discovery of novel benzamide-type cereblon binders for the design of PROTACs
Immunomodulatory imide drugs (IMiDs) such as thalidomide, pomalidomide, and
lenalidomide are the most common cereblon (CRBN) recruiters in proteolysis-targeting …
lenalidomide are the most common cereblon (CRBN) recruiters in proteolysis-targeting …
IPr* Thia–wingtip-flexible, sterically hindered, modular, N, C/S, C-chelating thiazole-donor N-heterocyclic carbene ligands
P Podchorodecka, B Dziuk, R Junga, R Szostak… - Dalton …, 2024 - pubs.rsc.org
N-Heterocyclic carbenes (NHCs) represent a pivotal class of ligands in coordination
chemistry owing to their unique electronic properties. In particular, hemilabile N-heterocyclic …
chemistry owing to their unique electronic properties. In particular, hemilabile N-heterocyclic …
Fragment‐Screening und schnelle mikromolare Detektion mit einem Benchtop‐NMR‐Spektrometer ermöglicht durch photoinduzierte Hyperpolarisation
GR Stadler, TF Segawa, M Bütikofer… - Angewandte …, 2023 - Wiley Online Library
Fragmentbasiertes Wirkstoffdesign ist eine gut etablierte Strategie für rationales
Arzneimitteldesign, wobei die Kernspinresonanzspektroskopie (NMR) auf …
Arzneimitteldesign, wobei die Kernspinresonanzspektroskopie (NMR) auf …
Synthesis and biochemical evaluation of new 3-amido-4-substituted monocyclic ß-lactams as inhibitors of penicillin-binding protein (s)
K Grabrijan, N Strašek Benedik, A Krajnc… - Acta …, 2024 - hrcak.srce.hr
Sažetak In the final phases of bacterial cell wall synthesis, penicillin-binding proteins (PBPs)
catalyze the cross-linking of peptidoglycan. For many decades, effective and non-toxic β …
catalyze the cross-linking of peptidoglycan. For many decades, effective and non-toxic β …
[PDF][PDF] Синтез та біологічна активність похідних фуранкарбонових кислот
Ю Матійчук - Annals of pharmaceutical faculty. April, 2021 - library.dmed.org.ua
АНОТАЦІЯ Матійчук ЮЕ Синтез та біологічна активність похідних фуранкарбонових
кислот.–Кваліфікаційна наукова праця на правах рукопису. Дисертація на здобуття …
кислот.–Кваліфікаційна наукова праця на правах рукопису. Дисертація на здобуття …