Neural network approaches for soft biological tissue and organ simulations

MS Sacks, S Motiwale… - Journal of …, 2022 - asmedigitalcollection.asme.org
Given the functional complexities of soft tissues and organs, it is clear that computational
simulations are critical in their understanding and for the rational basis for the development …

A review of polymeric heart valves leaflet geometric configuration and structural optimization

Y Wu, J Zhou, T Li, L Chen, Y Xiong… - Computer Methods in …, 2024 - Taylor & Francis
Valvular heart disease (VHD) is a major cause of loss of physical function, quality of life and
longevity, and its prevalence is growing worldwide due to increased survival rates and an …

GRIDS-Net: Inverse shape design and identification of scatterers via geometric regularization and physics-embedded deep learning

S Nair, TF Walsh, G Pickrell, F Semperlotti - Computer Methods in Applied …, 2023 - Elsevier
This study presents a deep learning based methodology for both remote sensing and design
of acoustic scatterers. The ability to determine the shape of a scatterer, either in the context …

Cardiac valve scaffold design: Implications of material properties and geometric configuration on performance and mechanics

DD Pedersen, S Kim, A D'Amore… - Journal of the Mechanical …, 2023 - Elsevier
Abstract Development of tissue engineered scaffolds for cardiac valve replacement is
nearing clinical translation. While much work has been done to characterize mechanical …

Fluid–structure interaction methods for the progressive anatomical and artificial aortic valve stenosis

M Nowak, E Divo, WP Adamczyk - International Journal of Mechanical …, 2022 - Elsevier
Cardiovascular system diseases, as aortic valve stenosis, are the main cause of mortality
and morbidity among patients. There is still a room for enhancement of the diagnostic and …

Functional mechanical behavior of the murine pulmonary heart valve

X Feng, Y Liu, D Kamensky, DW McComb… - Scientific Reports, 2023 - nature.com
Genetically modified mouse models provide a versatile and efficient platform to extend our
understanding of the underlying disease processes and evaluate potential treatments for …

Computational analysis of heart valve growth and remodeling after the Ross procedure

E Middendorp, F Braeu, FPT Baaijens… - … and modeling in …, 2024 - Springer
During the Ross procedure, an aortic heart valve is replaced by a patient's own pulmonary
valve. The pulmonary autograft subsequently undergoes substantial growth and remodeling …

Leveraging code generation for transparent immersogeometric fluid–structure interaction analysis on deforming domains

GE Neighbor, H Zhao, M Saraeian, MC Hsu… - Engineering with …, 2023 - Springer
Code generation technology has been transformative to the field of numerical partial
differential equations (PDEs), allowing domain scientists and engineers to automatically …

Simulation of mitral valve plasticity in response to myocardial infarction

BV Rego, AH Khalighi, JH Gorman III… - Annals of Biomedical …, 2023 - Springer
Left ventricular myocardial infarction (MI) has broad and debilitating effects on cardiac
function. In many cases, MI leads to ischemic mitral regurgitation (IMR), a condition …

Mechanical behaviors of high-strength fabric composite membrane designed for cardiac valve prosthesis replacement

H Zhou, Q Wu, L Wu, Y Zhao - Journal of the Mechanical Behavior of …, 2023 - Elsevier
Bovine pericardium has been commonly used as leaflets in cardiac valve prosthesis
replacement for decades because of its good short-term hemocompatibility and …