Cefiderocol appears promising, as it can overcome most β-lactam resistance mechanisms
(including β-lactamases, porin mutations, and efflux pumps). Resistance is uncommon …

Background Cefiderocol is a last resort option for carbapenem-resistant (CR) Gram-negative
bacteria, especially metallo-β-lactamase (MBL)-producing Pseudomonas aeruginosa and …

Carbapenem resistance in Gram-negative bacteria has come into sight as a serious global
threat. Carbapenem-resistant Gram-negative pathogens and their main representatives …

What is known and objective Acinetobacter baumannii is one of the most important
nosocomial pathogens with the ability to cause infections such as meningitis, pneumonia …

The discovery of antibiotics has revolutionized medicine and has changed medical practice,
enabling successful fighting of infection. However, quickly after the start of the antibiotic era …

Background: Acinetobacter baumannii is a common cause of multi-drug (MDR)-resistant
infections worldwide. The epidemiological and molecular characteristics of MDR-A …

Carbapenem-resistant Acinetobacter baumannii (CRAB) is becoming more widely
recognized as a serious cause of nosocomial infections, and colistin has been reintroduced …

Acinetobacter baumannii (AB) has evolved over the last decades as a major problem in
carbapenem-resistant gram-negative nosocomial infections, associated with high mortality …

Antibiotic resistance occurs when microorganisms resist the drugs used against the infection
caused by them and neutralize their effects over time using various mechanisms. These …

Emerging resistance to colistin in Acinetobacter baumannii clinical strains is concerning
because of the limited therapeutic choices for these important clinical pathogens. We …