Drug treatments for covid-19: living systematic review and network meta-analysis

RAC Siemieniuk, JJ Bartoszko, D Zeraatkar, E Kum… - bmj, 2020 - bmj.com
Objective To compare the effects of treatments for coronavirus disease 2019 (covid-19).
Design Living systematic review and network meta-analysis. Data sources WHO covid-19 …

The roles of calcium and ATP in the physiology and pathology of the exocrine pancreas

OH Petersen, JV Gerasimenko… - Physiological …, 2021 - journals.physiology.org
This review deals with the roles of calcium ions and ATP in the control of the normal
functions of the different cell types in the exocrine pancreas as well as the roles of these …

Interventions for treatment of COVID-19: A living systematic review with meta-analyses and trial sequential analyses (The LIVING Project)

S Juul, EE Nielsen, J Feinberg, F Siddiqui… - PLoS …, 2020 - journals.plos.org
Background Coronavirus disease 2019 (COVID-19) is a rapidly spreading disease that has
caused extensive burden to individuals, families, countries, and the world. Effective …

Orai1 inhibitors as potential treatments for pulmonary arterial hypertension

B Masson, H Le Ribeuz, J Sabourin, L Laubry… - Circulation …, 2022 - Am Heart Assoc
Background: Pulmonary arterial hypertension (PAH) is characterized by progressive distal
pulmonary artery (PA) obstruction, leading to right ventricular hypertrophy and failure …

Regulation of neuropathic pain by microglial Orai1 channels

S Tsujikawa, KE DeMeulenaere, MV Centeno… - Science …, 2023 - science.org
Microglia are important mediators of neuroinflammation, which underlies neuropathic pain.
However, the molecular checkpoints controlling microglial reactivity are not well-understood …

Interventions for treatment of COVID-19: of a living systematic review with meta-analyses and trial sequential analyses (The LIVING Project)

S Juul, EE Nielsen, J Feinberg, F Siddiqui… - PLoS …, 2021 - journals.plos.org
Background COVID-19 is a rapidly spreading disease that has caused extensive burden to
individuals, families, countries, and the world. Effective treatments of COVID-19 are urgently …

Current evidence for COVID-19 therapies: a systematic literature review

T Welte, LJ Ambrose, GC Sibbring… - European …, 2021 - Eur Respiratory Soc
Effective therapeutic interventions for the treatment and prevention of coronavirus disease
2019 (COVID-19) are urgently needed. A systematic review was conducted to identify …

[HTML][HTML] Auxora for the treatment of patients with acute pancreatitis and accompanying systemic inflammatory response syndrome: clinical development of a calcium …

C Bruen, J Miller, J Wilburn, C Mackey, TL Bollen… - Pancreas, 2021 - journals.lww.com
Objectives To assess the safety of Auxora in patients with acute pancreatitis (AP), systemic
inflammatory response syndrome (SIRS), and hypoxemia, and identify efficacy endpoints to …

Calcium signals during SARS-CoV-2 infection: Assessing the potential of emerging therapies

S Berlansky, M Sallinger, H Grabmayr, C Humer… - Cells, 2022 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a positive-sense single-
stranded RNA virus that causes coronavirus disease 2019 (COVID-19). This respiratory …

[HTML][HTML] Efficacy and safety of current medications for treating severe and non-severe COVID-19 patients: an updated network meta-analysis of randomized placebo …

Q Cheng, J Chen, Q Jia, Z Fang, G Zhao - Aging (albany NY), 2021 - ncbi.nlm.nih.gov
Background: Many recent studies have investigated the role of drug interventions for
coronavirus disease 2019 (COVID-19) infection. However, an important question has been …