Biological molecules such as DNA, proteins, and lipids can be assembled into naturally
existing nanoparticles, such as bacterial viruses (also called bacteriophages or phages) …

Nucleic acid (NA) therapeutics are a rapidly growing class of biomedicines with the ability to
manipulate gene expression in potent and specific manner, and with the enormous potential …

Breast cancer (BC) is the most prevalent malignancy and the second leading cause of death
among women worldwide that is caused by numerous genetic and environmental factors …

The complexity of breast cancer includes many interacting biological processes, and
proteasome alpha (PSMA) subunits are reported to be involved in many cancerous …

Adeno-associated virus (AAV) vectors have gained tremendous attention as in vivo delivery
systems in gene therapy for inherited monogenetic diseases. First market approvals …

Viral vectors can generate high levels of recombinant protein expression providing the basis
for modern vaccine development. A large number of different viral vector expression systems …

Clinical data from over two decades, involving more than 3000 treated patients, demonstrate
that adeno‐associated virus (AAV) gene therapy is a safe, effective, and well‐tolerated …

Breast carcinoma has one of the highest incidence rates (11.7%), with significant clinical
heterogeneity. Although conventional chemotherapy and surgical resection are the current …

Drug delivery to tumor sites using nanotechnology has been demonstrated to overcome the
drawbacks of conventional anticancer drugs. Altering the surface shape and geometry of …

Although the inhibition of acid ceramidase (AC) is known to induce antitumor effects in
various cancers, there are few reports in pancreatic cancer, and the underlying mechanisms …