Abstract Structure‐based mutational analysis of serine protease specificity has produced a
large database of information useful in addressing biological function and in establishing a …

Staphylococcus aureus is an important pathogen of humans and livestock. It causes a
diverse array of diseases, ranging from relatively harmless localized skin infections to life …

Patients with atopic dermatitis (AD) have an abnormal skin barrier and are frequently
colonized by S. aureus. In this study we investigated if S. aureus penetrates the epidermal …

Exfoliative toxin A, produced by Staphylococcus aureus, causes blisters in bullous impetigo
and its more generalized form, staphylococcal scalded-skin syndrome 1, 2, 3. The toxin …

Pemphigus, Bullous Impetigo, and the Staphylococcal Scalded-Skin Syndrome | New England
Journal of Medicine Skip to main content Access provided byMGH The New England Journal of …

The exfoliative (epidermolytic) toxins of Staphylococcus aureus are the causative agents of
the staphylococcal scalded-skin syndrome (SSSS), a blistering skin disorder that …

Much of the original research on desmosomes and their biochemical components was
through analysis of skin and mucous membranes. The identification of desmogleins 1 and 3 …

We identified a novel pathogenicity island in Staphylococcus aureus which contains open
reading frames (ORFs) similar to the exfoliative toxin (ET) gene, glutamyl endopeptidase …

The staphylococcal accessory regulator (encoded by sarA) is an important global regulator
of virulence factor biosynthesis in Staphylococcus aureus. To further characterize its role in …

Staphylococcal scalded skin syndrome (SSSS) is a common disorder that is usually seen in
infants and children and rarely seen in adults. SSSS usually presents with a prodrome of …