[HTML][HTML] Cognitive impairment in schizophrenia: aetiology, pathophysiology, and treatment
RA McCutcheon, RSE Keefe, PK McGuire - Molecular psychiatry, 2023 - nature.com
Cognitive deficits are a core feature of schizophrenia, account for much of the impaired
functioning associated with the disorder and are not responsive to existing treatments. In this …
functioning associated with the disorder and are not responsive to existing treatments. In this …
[HTML][HTML] Genetic variation, brain, and intelligence differences
Individual differences in human intelligence, as assessed using cognitive test scores, have a
well-replicated, hierarchical phenotypic covariance structure. They are substantially stable …
well-replicated, hierarchical phenotypic covariance structure. They are substantially stable …
[HTML][HTML] Biological and environmental predictors of heterogeneity in neurocognitive ageing: Evidence from Betula and other longitudinal studies
Individual differences in cognitive performance increase with advancing age, reflecting
marked cognitive changes in some individuals along with little or no change in others …
marked cognitive changes in some individuals along with little or no change in others …
[HTML][HTML] Evaluating the efficacy and mechanism of metformin targets on reducing Alzheimer's disease risk in the general population: a Mendelian randomisation study
Aims/hypothesis Metformin use has been associated with reduced incidence of dementia in
diabetic individuals in observational studies. However, the causality between the two in the …
diabetic individuals in observational studies. However, the causality between the two in the …
[HTML][HTML] Association of APOE ε4 genotype and lifestyle with cognitive function among Chinese adults aged 80 years and older: A cross-sectional study
Background Apolipoprotein E (APOE) ε4 is the single most important genetic risk factor for
cognitive impairment and Alzheimer disease (AD), while lifestyle factors such as smoking …
cognitive impairment and Alzheimer disease (AD), while lifestyle factors such as smoking …
Discovery of shared genomic loci using the conditional false discovery rate approach
In recent years, genome-wide association study (GWAS) sample sizes have become larger,
the statistical power has improved and thousands of trait-associated variants have been …
the statistical power has improved and thousands of trait-associated variants have been …
Genetic relationships between attention-deficit/hyperactivity disorder, autism spectrum disorder, and intelligence
S Rao, A Baranova, Y Yao, J Wang, F Zhang - Neuropsychobiology, 2022 - karger.com
Introduction: Attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorder
(ASD) commonly co-occur; both traits exert an influence on intelligence scores. Genetic …
(ASD) commonly co-occur; both traits exert an influence on intelligence scores. Genetic …
[PDF][PDF] Human microglia maturation is underpinned by specific gene regulatory networks
Microglia phenotypes are highly regulated by the brain environment, but the transcriptional
networks that specify the maturation of human microglia are poorly understood. Here, we …
networks that specify the maturation of human microglia are poorly understood. Here, we …
[HTML][HTML] Effect of sleep and mood on academic performance—at interface of physiology, psychology, and education
KJ Mehta - Humanities and Social Sciences Communications, 2022 - nature.com
Academic achievement and cognitive functions are influenced by sleep and mood/emotion.
In addition, several other factors affect learning. A coherent overview of the resultant …
In addition, several other factors affect learning. A coherent overview of the resultant …
Cognitive ability and education: How behavioural genetic research has advanced our knowledge and understanding of their association
Cognitive ability and educational success predict positive outcomes across the lifespan,
from higher earnings to better health and longevity. The shared positive outcomes …
from higher earnings to better health and longevity. The shared positive outcomes …