Naphthyridine-Based Electron Push–Pull-Type Amine-Reactive Fluorescent Probe for Sensing Amines and Proteins in Aqueous Media

T Umeno, L Muroi, Y Kayama, K Usui… - Bioconjugate …, 2023 - ACS Publications
In bioengineering, fluorescent amine-reactive probes are invaluable for the detection of
amine species. In particular, targeting probes for lysine, which has a free amino group in …

Basic Fluorescent Protonation-Type pH Probe Sensitive to Small ΔpKa of Methanol and Ethanol

T Umeno, R Seto, S Matsumoto, M Fujihara… - Analytical …, 2022 - ACS Publications
An optical pH probe is a simple and effective tool for determining an accurate pH value in its
localized area. However, basic pH probes with p K BH+ values above 8 have rarely been …

A Cys-regulated two-photon lysosomal targetable fluorescent probe and its application for the diagnosis of kidney diseases

Y Tang, J Peng, R Guo, H Lu, W Lin - Journal of Luminescence, 2023 - Elsevier
Cysteine (Cys) is a small-molecule amino acid containing sulfhydryl group, which play a
crucial role in many physiological and pathological processes. Detection of Cys closely …

Photoisomerization of “Partially Embedded Dihydropyridazine” with a Helical Structure

K Usui, A Amano, K Murayama… - … A European Journal, 2023 - Wiley Online Library
Herein, we report the synthesis of two “partially embedded fused‐dihydropyridazine N‐aryl
aza [5] helicene derivatives”(PDHs) and the demonstration of their intrinsic photo‐triggered …

Synthesis and Characterization of Emissive 1, 9, 10-Anthyridine Derivatives with Donor and Acceptor Groups

Y Fuchi, K Ikeno, M Fujihara, T Umeno… - Available at SSRN … - papers.ssrn.com
Abstract Push-pull-type emissive 1, 9, 10-anthyridine derivatives incorporating bis-
trifluoromethyl and amino (hydroxy) groups were designed and synthesized through the ring …

ドナー・アクセプター型分子の特性を利用した分析試薬の開発

梅野智大 - YAKUGAKU ZASSHI, 2024 - jstage.jst.go.jp
Summary π-Extended donor–acceptor (D–A)-type molecules, which bear both electron-
donor and electron-acceptor substituents on the backbone, exhibit unique optical properties …