Midbrain dopamine neurons deteriorate in Parkinson's disease (PD) that is a progressive
neurodegenerative movement disorder. No cure is available that would stop the …

Cerebral dopamine neurotrophic factor (CDNF) is an endogenous protein in humans and
other vertebrates, and it has been shown to have protective and restorative effects on cells in …

Background Cerebral dopamine neurotrophic factor (CDNF) is an unconventional
neurotrophic factor that protects dopamine neurons and improves motor function in animal …

Cerebral dopamine neurotrophic factor (CDNF) is a neurotrophic factor that has beneficial
effects on dopamine neurons in both in vitro and in vivo models of Parkinson's disease (PD) …

Neurotrophic factors (NTFs) play an important role in maintaining homeostasis of the central
nervous system (CNS) by regulating the survival, differentiation, maturation, and …

Movement disorders are neurological conditions characterized by involuntary motor
movements, such as dystonia, ataxia, chorea myoclonus, tremors, Huntington's disease …

In addition to the well-known degeneration of midbrain dopaminergic neurons, enteric
neurons can also be affected in neurodegenerative disorders such as Parkinson's disease …

Cerebral dopamine neurotrophic factor (CDNF) is an unconventional neurotrophic factor that
is a disease-modifying drug candidate for Parkinson's disease. CDNF has pleiotropic …

Parkinson's disease (PD) is a progressive neurodegenerative disease characterized by
gradual loss of midbrain dopamine neurons, leading to impaired motor function. Preclinical …

α-synuclein (α-syn) is an intrinsically disordered protein abundant in the central nervous
system. Physiologically, the protein regulates vesicle trafficking and neurotransmitter release …