The physics of functional magnetic resonance imaging (fMRI)

RB Buxton - Reports on Progress in Physics, 2013 - iopscience.iop.org
Functional magnetic resonance imaging (fMRI) is a methodology for detecting dynamic
patterns of activity in the working human brain. Although the initial discoveries that led to …

What's new in neuroimaging methods?

PA Bandettini - Annals of the New York Academy of Sciences, 2009 - Wiley Online Library
The rapid advancement of neuroimaging methodology and its growing availability has
transformed neuroscience research. The answers to many questions that we ask about how …

Separation of fNIRS signals into functional and systemic components based on differences in hemodynamic modalities

T Yamada, S Umeyama, K Matsuda - PloS one, 2012 - journals.plos.org
In conventional functional near-infrared spectroscopy (fNIRS), systemic physiological
fluctuations evoked by a body's motion and psychophysiological changes often contaminate …

Nonlinear coupling between cerebral blood flow, oxygen consumption, and ATP production in human visual cortex

AL Lin, PT Fox, J Hardies… - Proceedings of the …, 2010 - National Acad Sciences
The purpose of this study was to investigate activation-induced hypermetabolism and
hyperemia by using a multifrequency (4, 8, and 16 Hz) reversing-checkerboard visual …

Non-BOLD contrast for laminar fMRI in humans: CBF, CBV, and CMRO2

L Huber, K Uludağ, HE Möller - Neuroimage, 2019 - Elsevier
Functional magnetic resonance imaging (fMRI) using the blood oxygenation level-
dependent (BOLD) contrast indirectly probes neuronal activity changes via evoked cerebral …

Negative BOLD with large increases in neuronal activity

U Schridde, M Khubchandani, JE Motelow… - Cerebral …, 2008 - academic.oup.com
Blood oxygen level–dependent (BOLD) functional magnetic resonance imaging (fMRI) is
widely used in neuroscience to study brain activity. However, BOLD fMRI does not measure …

MRI techniques to measure arterial and venous cerebral blood volume

J Hua, P Liu, T Kim, M Donahue, S Rane, JJ Chen… - Neuroimage, 2019 - Elsevier
The measurement of cerebral blood volume (CBV) has been the topic of numerous
neuroimaging studies. To date, however, most in vivo imaging approaches can only …

Simulation study of brain blood flow regulation by intra-cortical arterioles in an anatomically accurate large human vascular network. Part II: flow variations induced by …

S Lorthois, F Cassot, F Lauwers - Neuroimage, 2011 - Elsevier
In a companion paper (Lorthois et al., Neuroimage, in press), we perform the first simulations
of blood flow in an anatomically accurate large human intra-cortical vascular network …

Cerebral blood volume MRI with intravascular superparamagnetic iron oxide nanoparticles

SG Kim, N Harel, T Jin, T Kim, P Lee… - NMR in …, 2013 - Wiley Online Library
The cerebral blood volume (CBV) is a crucial physiological indicator of tissue viability and
vascular reactivity. Thus, noninvasive CBV mapping has been of great interest. For this …

Dynamic model for the tissue concentration and oxygen saturation of hemoglobin in relation to blood volume, flow velocity, and oxygen consumption: Implications for …

S Fantini - Neuroimage, 2014 - Elsevier
This article presents a dynamic model that quantifies the temporal evolution of the
concentration and oxygen saturation of hemoglobin in tissue, as determined by time-varying …