MicroRNAs as potential biomarkers for diagnosis of attention deficit hyperactivity disorder

B Martinez, PV Peplow - Neural regeneration research, 2023 - journals.lww.com
Inappropriate levels of hyperactivity, impulsivity, and inattention characterize attention deficit
hyperactivity disorder, a common childhood-onset neuropsychiatric disorder. The cognitive …

The mystique of epigenetic regulation: the remarkable case of a human noncoding RNA, nc886

YS Lee, YS Lee - Epigenomics, 2024 - Taylor & Francis
ABSTRACT nc886 is a regulatory noncoding RNA that is transcribed by RNA polymerase III
(Pol III), is variably expressed in different biological contexts, and plays roles in inflammation …

MicroRNAs serve as prediction and treatment-response biomarkers of attention-deficit/hyperactivity disorder and promote the differentiation of neuronal cells by …

LJ Wang, HC Kuo, SY Lee, LH Huang, Y Lin… - Translational …, 2022 - nature.com
Attention-deficit/hyperactivity disorder (ADHD) is a highly heritable neurodevelopmental
disorder. This study aimed to examine whether miRNA expression abundance in total white …

Prenatal gene editing for neurodevelopmental diseases: Ethical considerations

RM Major, ET Juengst - The American Journal of Human Genetics, 2025 - cell.com
Neurodevelopmental diseases (NDDs) are notoriously difficult to treat because clinical
symptoms stem from developmental processes that begin before birth. Prenatal gene editing …

The Exon Junction Complex Factor RBM8A in Glial Fibrillary Acid Protein-Expressing Astrocytes Modulates Locomotion Behaviors

S Asthana, J Mott, M Tong, Z Pei, Y Mao - Cells, 2024 - mdpi.com
The role of RNA Binding Motif Protein 8a (RBM8A), an exon junction complex (EJC)
component, in neurodevelopmental disorders has been increasingly studied for its crucial …

Unraveling the Role of miR-200b-3p in Attention-Deficit/Hyperactivity Disorder (ADHD) and Its Therapeutic Potential in Spontaneously Hypertensive Rats (SHR)

TM Chang, HL Lin, CC Tzang, JA Liang, TC Hsu… - Biomedicines, 2024 - mdpi.com
Attention-deficit/hyperactivity disorder (ADHD) is a prevalent neurodevelopmental disorder
in children with unknown etiology. Impaired learning ability was commonly reported in …

Zebrafish as an Emerging Model for Sarcopenia: Considerations, Current Insights, and Future Directions

S Callegari, F Mirzaei, L Agbaria, S Shariff… - International Journal of …, 2023 - mdpi.com
Sarcopenia poses a significant challenge to public health and can severely impact the
quality of life of aging populations. Despite extensive efforts to study muscle degeneration …

Exploring Association Between Serotonin and Neurogenesis Related Genes in Obsessive-Compulsive Disorder in Chinese Han People: Promising Association …

M Deng, Y Wang, S Yu, Q Fan, J Qiu, Z Wang… - Frontiers in …, 2022 - frontiersin.org
Obsessive-compulsive disorder (OCD) is a deliberating disorder with complex genetic and
environmental etiologies. Hypotheses about OCD mainly include dysregulated …

Dysregulation of miR‐146a in human milk of mothers having children with autism

NA Meguid, M Hemimi, M Rashad… - International Journal …, 2024 - Wiley Online Library
Autism spectrum disorder (ASD) is a set of neurobehavioral manifestations that impose poor
social interaction and stereotyped repetitive patterns. Several mircoRNA (miRNA) …

Identification of Hsa-miR-92a-3p as a novel biomarker and PIK3R1 as a key regulatory gene to combat with the diagnostic patterns of autism spectrum disorders

P Trivedi, SS Dubey, P Singh, P Srivastava - Materials Today: Proceedings, 2022 - Elsevier
In this study, two individual RNA-Seq datasets viz. GSE64018 and GSE62098 were selected
from the Gene Expression Omnibus (GEO) database having samples of ASD and healthy …