Neurodevelopmental disorders (NDDs), including intellectual disability (ID) and autism
spectrum disorders (ASD), are a large group of disorders in which early insults during brain …

The epigenetic machinery in conjunction with the transcriptional machinery is responsible
for maintaining genome-wide chromatin states and dynamically regulating gene expression …

There is a consensus in the field that microglia play a prominent role in neurodevelopmental
processes like synaptic pruning and neuronal network maturation. Thus, a current …

Neurodevelopmental disorders (NDDs) and cancer share proteins, pathways, and
mutations. Their clinical symptoms are different. However, individuals with NDDs have …

Methods: We conducted a literature search (2005-2020) using online database PubMed,
specifically for studies related to the clinical aspects of intellectual disability as they apply to …

Neurons are dynamic cells that respond and adapt to stimuli throughout their long
postmitotic lives. The structural and functional plasticity of neurons requires the regulated …

The effects of environmental factors and epigenetics on health and disease development
are complex and interconnected. Environmental factors encompass external influences like …

Intellectual disability (ID) is a genetically and clinically heterogeneous disorder,
characterized by limited cognitive abilities and impaired adaptive behaviors. In recent years …

Interactions between chromatin-associated proteins and the histone landscape play major
roles in dictating genome topology and gene expression. Cancer-specific fusion …

Autism spectrum disorder (ASD) and intellectual disability (ID) are heterogenous and
prevalent conditions which may occur in isolation or as a co-morbidity. Psychiatric co …