Genus Ophiorrhiza: A Review of Its Distribution, Traditional Uses, Phytochemistry, Biological Activities and Propagation

M Taher, SS Shaari, D Susanti, D Arbain, ZA Zakaria - Molecules, 2020 - mdpi.com
Almost 50 species of Ophiorrhiza plants were reviewed in this work and the main objective is
to critically analyse their distribution, phytochemical content, biological activity, and …

Recent studies on chemical constituents of Ophiorrhiza plants

M Kitajima - Journal of Natural Medicines, 2022 - Springer
Abstract Ophiorrhiza plants (Family Rubiaceae) are known to produce diverse
monoterpenoid indole alkaloids including camptothecin with potent antitumor activity. This …

Bioinspired transformations using strictosidine aglycones: divergent total syntheses of monoterpenoid indole alkaloids in the early stage of biosynthesis

J Sakamoto, H Ishikawa - Chemistry–A European Journal, 2022 - Wiley Online Library
A series of bioinspired transformations that are applied to convert strictosidine aglycones
into monoterpenoid indole alkaloids is reported. The highly reactive key intermediates …

Recent progress in the chemistry of the monoterpenoid indole alkaloids

JE Saxton - Natural Product Reports, 1995 - pubs.rsc.org
Recent reviews include a general one on indolocarbazoles, l and a specific one devoted to
9-hydroxyellipti~ ine.~ Another review, in which the sources, antitumour activity, and clinical …

A Cyclopeptide and a Tetrahydroisoquinoline Alkaloid from Ophiorrhiza nutans

T Onozawa, M Kitajima, N Kogure… - Journal of Natural …, 2017 - ACS Publications
A new cyclopeptide, ophiorrhisine A (1), a new tetrahydroisoquinoline alkaloid, 7′, 10-dide-
O-methylcephaeline (2), two known β-carboline alkaloids, and four known …

Production of the Anticancer Compound Camptothecin in Root and Hairy Root Cultures of Ophiorrhiza mungos L.

B Wetterauer, E Wildi, M Wink - Biotechnological Approaches for Medicinal …, 2018 - Springer
Camptothecin (CPT), a modified monoterpene indole alkaloid, is a well-known
antineoplastic agent. A comparison of 25 different transformed root culture lines of …

Total synthesis of (−)-normalindine via addition of metalated 4-methyl-3-cyanopyridine to an enantiopure sulfinimine

FA Davis, JY Melamed, SS Sharik - The Journal of organic …, 2006 - ACS Publications
Total Synthesis of (−)-Normalindine via Addition of Metalated 4-Methyl-3-cyanopyridine to an
Enantiopure Sulfinimine | The Journal of Organic Chemistry ACS ACS Publications C&EN …

β-Carboline-type indole alkaloid glycosides from Ophiorrhiza trichocarpon

M Kitajima, S Ohara, N Kogure, D Santiarworn… - Tetrahedron, 2013 - Elsevier
Six new β-carboline-type indole alkaloid glycosides, ophiorrhisides A–F (1–6), were isolated
from Ophiorrhiza trichocarpon (Rubiaceae) collected in Thailand. Ophiorrhisides A (1) and B …

Inventory, constituents and conservation of biologically important Sumatran plants

D Arbain - Natural Product Communications, 2012 - journals.sagepub.com
Inventory, Constituents and Conservation of Biologically Important Sumatran Plants Page 1
Inventory, Constituents and Conservation of Biologically Important Sumatran Plants Dayar …

A Chiral Synthesis of the Strychnos and Ophiorrhiza Alkaloid Normalindine

M Ohba, H Kubo, H Ishibashi - Tetrahedron, 2000 - Elsevier
A full account of the first chiral synthesis of (−)-normalindine [(−)-4], an
indolopyridonaphthyridine alkaloid isolated from Strychnos johnsonii and Ophiorrhiza …