Gadolinium-based contrast agents (GBCAs) have transformed magnetic resonance imaging
(MRI) by facilitating the use of contrast-enhanced MRI to allow vital clinical diagnosis in a …

The systemic and organ-specific human fibrotic disorders collectively represent one of the
most serious health problems world-wide causing a large proportion of the total world …

Nephrogenic systemic fibrosis (NSF) is an iatrogenic scleroderma-like fibrosing systemic
disorder occurring in patients with severe or end-stage renal disease. It was established as …

Nephrogenic systemic fibrosis (NSF) occurs in patients with advanced chronic kidney
disease (CKD) or acute renal failure, most commonly following exposure to gadolinium …

Gadolinium-based contrast agents (GBCAs), once believed to be safe for patients with renal
disease, have been strongly associated with nephrogenic systemic fibrosis (NSF), a severe …

Background There is an ongoing scientific debate about the degree and clinical importance
of gadolinium deposition in the brain and other organs after administration of gadolinium …

Nephrogenic systemic fibrosis (NSF) is an iatrogenic fibrosing disorder that primarily affects
individuals with chronic kidney disease (CKD) following exposure to gadolinium-based …

The use of nanovesicles with encapsulated Gd as magnetic resonance (MR) contrast agents
has largely been ignored due to the detrimental effects of the slow water exchange rate …

Nephrogenic systemic fibrosis (NSF) is a potentially severe systemic disease typically
characterized by fibrosis of the skin and connective tissues. The etiology of NSF is still …

These observations provide a new paradigm for understanding the relationship between
immunity/inflammation and fibrosis. New therapeutics, including TLR agonists and …