AI/ML-driven advances in untargeted metabolomics and exposomics for biomedical applications

LM Petrick, N Shomron - Cell Reports Physical Science, 2022 - cell.com
Metabolomics describes a high-throughput approach for measuring a repertoire of
metabolites and small molecules in biological samples. One utility of untargeted …

Gut Immunobiosis and Biomodulators

VL Miniello, A Miniello, L Ficele, A Skublewska-D'Elia… - Nutrients, 2023 - mdpi.com
The human gastrointestinal (GI) tract hosts complex and dynamic populations of
microorganisms (gut microbiota) in advantageous symbiosis with the host organism through …

Dual UHPLC-HRMS metabolomics and lipidomics and automated data processing workflow for comprehensive high-throughput gut phenotyping

P Vangeenderhuysen, J Van Arnhem… - Analytical …, 2023 - ACS Publications
In recent years, feces has surfaced as the matrix of choice for investigating the gut
microbiome-health axis because of its non-invasive sampling and the unique reflection it …

Xylan Prebiotics and the Gut Microbiome Promote Health and Wellbeing: Potential Novel Roles for Pentosan Polysulfate

MM Smith, J Melrose - Pharmaceuticals, 2022 - mdpi.com
This narrative review highlights the complexities of the gut microbiome and health-promoting
properties of prebiotic xylans metabolized by the gut microbiome. In animal husbandry …

Integration of omics approaches enhances the impact of scientific research in environmental applications

A Gruszecka-Kosowska, A Ampatzoglou… - International Journal of …, 2022 - mdpi.com
Research in the field of environmental sciences currently attracts a lot of attention. As the
pollution of the environment is already pushing the earth beyond its homeostasis state …

[HTML][HTML] Exploration and optimization of extraction, analysis and data normalization strategies for mass spectrometry-based DNA adductome mapping and modeling

M De Graeve, E Van de Walle, T Van Hecke… - Analytica Chimica …, 2023 - Elsevier
Although interest in characterizing DNA damage by means of DNA adductomics has
substantially grown, the field of DNA adductomics is still in its infancy, with room for …

Trial in Elderly with Musculoskeletal Problems due to Underlying Sarcopenia—Faeces to Unravel the Gut and Inflammation Translationally (TEMPUS-FUGIT): protocol …

L Lapauw, J Dupont, N Amini, L Vercauteren… - BMC geriatrics, 2023 - Springer
Background Gut microbiota (GM) might play a role in muscle metabolism and physiological
processes through a hypothesized gut-muscle axis, influencing muscle mass and function …

A Dual UHPLC-HRMS-Based Fecal Metabolomics and Lipidomics Analysis and Automated Data Processing Pipeline for Comprehen-sive Gut Phenotyping

P Vangeenderhuysen, J Van Arnhem, B Pomian… - 2023 - chemrxiv.org
In recent years, feces has surfaced as the matrix of choice for investigating the gut
microbiome-health axis because of its non-invasive sampling and the unique reflection it …

Ontwikkelen van een omgevingsindicatorenset en het in kaart brengen van biomerkers om de gezondheidsimpact van de klimaatverandering te monitoren

K Van de Vel, V Verheyen, F Lefebre… - 2022 - archief.algemeen.omgeving …
Het Intergovernmental Panel on Climate Change (IPCC), van de United Nations geeft als
definitie voor klimaatverandering “any change in climate over time whether due to natural …

[HTML][HTML] FLEXiGUT: investigating the importance of the exposome in the development and progression of chronic low-grade gut inflammation

R Peró Gascón, E Maris, Á Cseresznye… - … Days+ Exposome-NL …, 2023 - biblio.ugent.be
Exposure to environmental and dietary contaminants, such as toxins, man-made chemicals
and air pollution, is suspected to disturb gut homeostasis and have a negative impact on …