Gap genes are involved in segment determination during the early development of the fruit
fly Drosophila melanogaster as well as in other insects. This review attempts to synthesize …

The red flour beetle Tribolium castaneum has emerged as an important insect model system
for a variety of topics. With respect to studying gene function, it is second only to the vinegar …

▪ Abstract Over the past dozen years, studies comparing the expression of orthologues of the
Drosophila segmentation genes among various insects have served to broaden our view of …

Genetic screens are powerful tools to identify the genes required for a given biological
process. However, for technical reasons, comprehensive screens have been restricted to …

Most of our knowledge about the mechanisms of segmentation in arthropods comes from
work on Drosophila melanogaster. In recent years it has become clear that this mechanism …

In Drosophila, a hierarchy of maternal, gap, pair-rule, and segment polarity gene interactions
regulates virtually simultaneous blastoderm segmentation. For the last decade, studies have …

The formation of somites, reiterated structures that will give rise to vertebrae and muscles, is
thought to be dependent upon a molecular oscillator that may involve the Notch pathway …

The three major taxa with metameric segmentation (annelids, arthropods, and chordates)
appear to use three very different molecular strategies to generate segments. However …

A fundamental characteristic of the arthropod body plan is its organization in metameric units
along the anterior–posterior axis. The segmental organization is laid down during early …

Arthropods, annelids and chordates all possess segments. It remains unclear, however,
whether the segments of these animals evolved independently or instead were derived from …