A new world syndrome of metabolic diseases with a genetic and evolutionary basis

KM Weiss, RF Ferrell, CL Hanis - American journal of physical …, 1984 - Wiley Online Library
Currently, many Amerindian peoples, including European‐Amerindian admixed groups
such as Mexicans, are experiencing a major epidemic of a series of diseases which includes …

[图书][B] The liver: biology and pathobiology

IM Arias, HJ Alter, JL Boyer, DE Cohen, DA Shafritz… - 2020 - books.google.com
Bridging the gap between basic scientific advances and the understanding of liver disease—
the extensively revised new edition of the premier text in the field. The latest edition of The …

Deoxycholic acid and the pathogenesis of gall stones.

SN Marcus, KW Heaton - Gut, 1988 - ncbi.nlm.nih.gov
That deoxycholic acid (DCA) may havea role in cholesterol gall stone formation has been
discussed on several occasions'but authoritative reviews of gall stone pathogenesis fail to …

Gallbladder disease in the morbidly obese

JF Amaral, WR Thompson - The American journal of surgery, 1985 - Elsevier
During a 7 year period, 200 consecutive morbidly obese patients underwent a standardized
gastric exclusion procedure. Group A was composed of the first 120 patients and Group B of …

[HTML][HTML] Influence of nicotinic acid on metabolism of cholesterol and triglycerides in man

SM Grundy, HYL Mok, L Zech, M Berman - Journal of lipid research, 1981 - Elsevier
The mechanisms for the hypolipidemic action of nicotinic acid were examined in 12 patients
with hyperlipidemia. Most patients were studied in the hospital on a metabolic ward. The first …

Effects of obesity and caloric intake on biliary lipid metabolism in man.

LJ Bennion, SM Grundy - The Journal of Clinical …, 1975 - Am Soc Clin Investig
The effects of obesity and caloric intake on biliary lipid metabolism were investigated in a
series of related studies. The degree of saturation of gallbladder bile with cholesterol was …

Intestinal transit, deoxycholic acid and the cholesterol saturation of bile--three inter-related factors.

SN Marcus, KW Heaton - Gut, 1986 - gut.bmj.com
There is considerable evidence that the level of deoxycholic acid in the bile influences
biliary cholesterol saturation. Deoxycholic acid is formed in the colon and absorbed slowly …

Mechanisms of lithogenic bile formation in American Indian women with cholesterol gallstones

SM Grundy, AL Metzger, RD Adler - The Journal of clinical …, 1972 - Am Soc Clin Investig
Hepatic secretions of biliary lipids were estimated in 43 patients with and without cholesterol
gallstones. Studies were carried out by a marker dilution technique employing duodenal …

Effects of polyunsaturated fats on lipid metabolism in patients with hypertriglyceridemia.

SM Grundy - The Journal of Clinical Investigation, 1975 - Am Soc Clin Investig
Studies were carried out on the effects of polyunsaturated fats on lipid metabolism in 11
patients with hypertriglyceridemia. During cholesterol balance studies performed in eight …

Mechanism for the transit-induced increase in colonic deoxycholic acid formation in cholesterol cholelithiasis

LA Thomas, MJ Veysey, T Bathgate, A King, G French… - Gastroenterology, 2000 - Elsevier
Background & Aims: Many patients with cholesterol gallbladder stones (GBS) have a high
percentage of deoxycholic acid (DCA) in gallbladder bile (all of which are in the conjugated …