[HTML][HTML] Early life adversity during the infant sensitive period for attachment: Programming of behavioral neurobiology of threat processing and social behavior

M Opendak, E Gould, R Sullivan - Developmental cognitive neuroscience, 2017 - Elsevier
Animals, including humans, require a highly coordinated and flexible system of social
behavior and threat evaluation. However, trauma can disrupt this system, with the amygdala …

Oxytocin effects in schizophrenia: reconciling mixed findings and moving forward

ER Bradley, JD Woolley - Neuroscience & Biobehavioral Reviews, 2017 - Elsevier
Schizophrenia is a severe mental illness that causes major functional impairment. Current
pharmacologic treatments are inadequate, particularly for addressing negative and cognitive …

Oxytocin improves behavioral and electrophysiological deficits in a novel Shank3-deficient rat

H Harony-Nicolas, M Kay, J du Hoffmann, ME Klein… - Elife, 2017 - elifesciences.org
Mutations in the synaptic gene SHANK3 lead to a neurodevelopmental disorder known as
Phelan-McDermid syndrome (PMS). PMS is a relatively common monogenic and highly …

Effect of age and autism spectrum disorder on oxytocin receptor density in the human basal forebrain and midbrain

SM Freeman, MC Palumbo, RH Lawrence… - Translational …, 2018 - nature.com
The prosocial hormone oxytocin (OXT) has become a new target for research on the etiology
and treatment of autism spectrum disorder (ASD), a condition characterized by deficits in …

Hippocampal deficits in neurodevelopmental disorders

Y Li, M Shen, ME Stockton, X Zhao - Neurobiology of learning and memory, 2019 - Elsevier
Neurodevelopmental disorders result from impaired development or maturation of the
central nervous system. Both genetic and environmental factors can contribute to the …

[HTML][HTML] Long term effects of chronic intranasal oxytocin on adult pair bonding behavior and brain glucose uptake in titi monkeys (Plecturocebus cupreus)

R Arias-del Razo, MLV Vazquez, P Turcanu… - Hormones and …, 2022 - Elsevier
Intranasal oxytocin (IN OXT) administration has been proposed as a pharmacological
treatment for a range of biomedical conditions including neurodevelopmental disorders …

Advances in nonhuman primate models of autism: Integrating neuroscience and behavior

MD Bauman, CM Schumann - Experimental neurology, 2018 - Elsevier
Given the prevalence and societal impact of autism spectrum disorders (ASD), there is an
urgent need to develop innovative preventative strategies and treatments to reduce the …

Acute oxytocin improves memory and gaze following in male but not female nursery-reared infant macaques

EA Simpson, A Paukner, V Sclafani, SSK Kaburu… - …, 2017 - Springer
Rationale Exogenous oxytocin administration is widely reported to improve social cognition
in human and nonhuman primate adults. Risk factors of impaired social cognition, however …

Maximizing valid eye-tracking data in human and macaque infants by optimizing calibration and adjusting areas of interest

G Zeng, EA Simpson, A Paukner - Behavior Research Methods, 2024 - Springer
Remote eye tracking with automated corneal reflection provides insights into the emergence
and development of cognitive, social, and emotional functions in human infants and non …

Social touch alters newborn monkey behavior

EA Simpson, SE Maylott, RJ Lazo, KA Leonard… - Infant Behavior and …, 2019 - Elsevier
In humans, infants respond positively to slow, gentle stroking—processed by C-tactile (CT)
nerve fibers—by showing reductions in stress and increases in eye contact, smiling, and …