Peptide-based liquid droplets as emerging delivery vehicles

J Liu, E Spruijt, A Miserez, R Langer - Nature Reviews Materials, 2023 - nature.com
Peptides are small yet versatile building blocks of biomaterials. This Comment highlights
recent progress in the design of liquid-like microdroplets, or coacervates, based on peptides …

How to drink like a liposome

J Liu, BZ Tang - Nature Reviews Chemistry, 2023 - nature.com
How to drink like a liposome | Nature Reviews Chemistry Skip to main content Thank you for
visiting nature.com. You are using a browser version with limited support for CSS. To obtain …

Molecular logic operations from complex coacervation with aggregation-induced emission characteristics

J Liu, T Zhang, X Liu, JWY Lam, BZ Tang, Y Chau - Materials Horizons, 2022 - pubs.rsc.org
Leveraging complex coacervation of a polycation and a bivalent anion with aggregation-
induced emission characteristics, we accomplish eight basic logic operations with …

Construction of multiphasic membraneless organelles towards spontaneous spatial segregation and directional flow of biochemical reactions

F Zhorabek, MS Abesekara, J Liu, X Dai, J Huang… - Chemical …, 2023 - pubs.rsc.org
Many intracellular membraneless organelles (MLOs) appear to adapt a hierarchical
multicompartment organization for efficient coordination of highly complex reaction …

Biomaterial design inspired by membraneless organelles

J Liu, F Zhorabek, Y Chau - Matter, 2022 - cell.com
Membraneless organelles (MLOs) are phase-separated liquid compartments providing
spatiotemporal control of biomolecules and metabolism within cells. While MLOs exhibit …

Large-sized but ready to enter: Micron-sized liquid droplets for versatile intracellular delivery

J Liu, R Feng, Y Chau - Matter, 2022 - cell.com
Nanoparticles have been largely designed and exploited for intracellular delivery of
biomacromolecules, classically via endocytosis pathways. A recent work published by …

Give crucibles to a prokaryote

J Liu, T Zhang, X Liu, BZ Tang - Matter, 2022 - cell.com
Prokaryotes are hodgepodge-like" bags" with minimal intracellular organization. Recently in
Angewandte Chemie International Edition, Xia et al. synthesized artificial membraneless …

Liquid capsules for gastrointestinal drug delivery

J Liu, SL Perry, BZ Tang, MV Tirrell - Matter, 2022 - cell.com
Recently, Margossian et al. reported pH-responsive complex coacervates formed by a
polyzwitterion and a polyelectrolyte in Nature Communications, which remain intact under …

From chemistry to dentistry: Paving my uncommon way to Harvard School of Dental Medicine as a materials scientist

J Liu - Matter, 2022 - cell.com
Being an underrepresented minority with a unique background in a research community can
be peculiar and double-edged. Here, Dr. Jianhui Liu, a new Post-doctoral Fellow at Harvard …

How art impacts my science

J Liu - Matter, 2022 - cell.com
How art impacts my science Page 1 Matter of Opinion How art impacts my science Jianhui
Liu1,2,3,4,* Art and science are never incompatible. In this Matter of Opinion, Dr. Jianhui Liu …