Background: The management of acute and chronic pain for individuals living with sickle cell
disease (SCD) is a clinical challenge. This reflects the paucity of clinical SCD pain research …

Early diagnosis, treatment, and prevention of a vaso‐occlusive crisis (VOC) are critical to the
management of patients with sickle cell disease. It is essential to differentiate between VOC …

Executive summary All over the world, people with sickle cell disease (an inherited
condition) have premature deaths and preventable severe chronic complications, which …

Sickle-cell disease is one of the most common severe monogenic disorders in the world.
Haemoglobin polymerisation, leading to erythrocyte rigidity and vaso-occlusion, is central to …

Delayed hemolytic transfusion reaction (DHTR) is one of the most feared complications of
sickle‐cell disease (SCD). We retrospectively analyzed the clinical and biological features …

Background Patients who develop sickle cell disease (SCD) nephropathy are at a high risk
for mortality. The pathophysiology of vaso-occlusive pain crisis may contribute to acute …

The earliest symptom of glomerular injury in patients with sickle cell disease (SCD) is
microalbuminuria. The effect of hydroxyurea (HU) on urine albumin-to-creatinine ratio (ACR) …

Background Vaso-occlusive crisis (VOC), hallmark of sickle-cell disease (SCD), is the first
cause of patients' Emergency-Room admissions and hospitalizations. Acute chest syndrome …

Pain is the hallmark of sickle cell disease in children and adolescents. Many children seek
relief from their pain in the emergency department. These visits have historically been …

Clinical management of adult sickle-cell disease : Current Opinion in Hematology Clinical
management of adult sickle-cell disease : Current Opinion in Hematology Log in or Register …