Macrophage migration inhibitory factor (MIF) is a cytokine expressed in various cell types,
including hematopoietic, epithelial, endothelial, mesenchymal and neuronal cells. Altered …

Strong evidence has been presented linking chronic inflammation to the onset and
pathogenesis of cancer. The multifunctional pro‐inflammatory protein macrophage migration …

The macrophage migration inhibitory factor (MIF), an inflammatory cytokine, is
overexpressed in many solid tumors and is associated with poor prognosis. We previously …

BACKGROUND: Isothiocyanates are phytochemicals with a broad array of effects in
biological systems. Bioactivity includes the stimulation of cellular antioxidant systems …

A high consumption of vegetables belonging to the Brassicaceae family has been related to
a lower incidence of chronic diseases including different kinds of cancer. These beneficial …

Dysregulation of innate immune responses can result in chronic inflammatory conditions.
Glucocorticoids, the current frontline therapy, are effective immunosuppressive drugs but …

Isothiocyanates, occurring in many dietary cruciferous vegetables, show interesting
chemopreventive activities against several chronic–degenerative diseases, including …

Owing to the prevalence of chronic inflammation and its related disorders, there is a demand
for novel therapeutic agents capable of preventing or suppressing inflammation. Natural …

The glucosinolate–myrosinase system is the main activated chemical defence present
among plants of the order Brassicales, which includes agriculturally important crucifer crops …

The mainstay of therapy for chronic kidney disease is control of blood pressure and
proteinuria through the use of angiotensin-converting enzyme inhibitors (ACE-Is) or …