Anti-obesity effects of metformin: a scoping review evaluating the feasibility of brown adipose tissue as a therapeutic target

K Ziqubu, SE Mazibuko-Mbeje, SXH Mthembu… - International Journal of …, 2023 - mdpi.com
Brown adipose tissue (BAT) is increasingly recognized as the major therapeutic target to
promote energy expenditure and ameliorate diverse metabolic complications. There is a …

[HTML][HTML] Climate change and obesity

CA Koch, P Sharda, J Patel, S Gubbi… - Hormone and …, 2021 - thieme-connect.com
Global warming and the rising prevalence of obesity are well described challenges of
current mankind. Most recently, the COVID-19 pandemic arose as a new challenge. We here …

The “irisin system”: From biological roles to pharmacological and nutraceutical perspectives

L Flori, L Testai, V Calderone - Life Sciences, 2021 - Elsevier
The scientific interest in irisin, a myokine discovered in 2012, has grown exponentially in
recent years. Irisin, which is mainly produced in skeletal muscle, influences the browning …

Irisin enhances longevity by boosting SIRT1, AMPK, autophagy and telomerase

B Sánchez, MF Muñoz-Pinto, M Cano - Expert Reviews in Molecular …, 2023 - cambridge.org
Ageing is characterised by the accumulation of molecular and cellular damage through time,
leading to a decline in physical and mental abilities. Currently, society has experienced a …

Polycystic ovary syndrome and adipose tissue

M Lemaitre, S Christin-Maitre, V Kerlan - Annales d'endocrinologie, 2023 - Elsevier
Polycystic ovary syndrome (PCOS) is the most common endocrine metabolic disorder in
women of reproductive age. Typically, it is associated with ovulatory dysfunction …

Brown fat triglyceride content is associated with cardiovascular risk markers in adults from a tropical region

M Monfort-Pires, G Regeni-Silva, P Dadson… - Frontiers in …, 2022 - frontiersin.org
Brown adipose tissue (BAT) is regarded as an interesting potential target for the treatment of
obesity, diabetes, and cardiovascular diseases, and the detailed characterization of its …

Molecular Imaging in Gynecology: Beyond Cancer

J Sebastiano, C Rodriguez, ZV Samuels… - Journal of Nuclear …, 2024 - jnm.snmjournals.org
Gynecological pathologies account for approximately 4.5% of the overall global disease
burden. Although cancers of the female reproductive system have understandably been the …

18F-FDG PET/CT technology for the assessment of brown adipose tissue: an updated review

M Ricci, MS De Feo, GM Granese… - Expert Review of …, 2023 - Taylor & Francis
Introduction This review provides an update of 18 F-fluorodeoxyglucose ([18F] FDG) for
Brown adipose tissue (BAT) activity quantification, whose role is not completely understood …

[HTML][HTML] Role of Brown Adipose Tissue in Metabolic Health and Efficacy of Drug Treatment for Obesity

NO Markina, GA Matveev, GG Zasypkin… - Journal of Clinical …, 2024 - mdpi.com
(1) Background: Brown adipose tissue (BAT) is responsible for non-shivering
thermogenesis, and its activation has become a new object as both a determinant of …

Intrinsic abnormalities of adipose tissue and adipose tissue dysfunction in PCOS

PM Spritzer, BR Santos, TM Fighera… - Polycystic Ovary …, 2022 - Elsevier
Polycystic ovary syndrome, characterized by ovarian dysfunction and androgen excess, is a
frequent and complex condition affecting women of reproductive age. Insulin resistance and …