An exceptional safety profile has been shown in a large number of cell therapy clinical trials
that use mesenchymal stromal cells (MSCs). However, reliable potency assays are still …

Haematopoietic stem and progenitor cell (HSPC) gene therapy has emerged as an effective
treatment modality for monogenic disorders of the blood system such as primary …

Hematopoietic stem-cell transplantation (hsct) is a medical procedure that consists of
infusing stem cells after a short course of chemotherapy or radiotherapy, or both. It can be …

Hepatic veno-occlusive disease (VOD) or sinusoidal obstruction syndrome (SOS) is a rare
complication characterized by hepatomegaly, right-upper quadrant pain, jaundice, and …

Patients undergoing solid-organ transplantation (SOT) or allogeneic hematopoietic cell
transplantation (HCT) are at increased risk for infectious complications. Community-acquired …

Hematotoxicity after chimeric antigen receptor (CAR) T-cell therapy is associated with
infection and death but management remains unclear. We report results of 31 patients …

Allogeneic haematopoietic cell transplantation (allo-HCT) remains the only curative
approach in myelofibrosis (MF). Despite advances over recent decades, relapse and non …

Specific protocols define eligibility, conditioning, donor selection, graft composition and
prophylaxis of graft vs. host disease for children and young adults undergoing hematopoietic …

Allogeneic hematopoietic stem cell transplantation (allo-HSCT) represents a potentially
curative strategy for many oncological and non-oncological diseases, but it is associated …

Background Activated phosphoinositide 3-kinase delta syndrome (APDS) is a combined
immunodeficiency with a heterogeneous phenotype considered reversible by allogeneic …