Microtubules as a potential platform for energy transfer in biological systems: a target for implementing individualized, dynamic variability patterns to improve organ …

Y Ilan - Molecular and Cellular Biochemistry, 2023 - Springer
Variability characterizes the complexity of biological systems and is essential for their
function. Microtubules (MTs) play a role in structural integrity, cell motility, material transport …

The cytoskeleton as regulator of cell signaling pathways

O Moujaber, U Stochaj - Trends in biochemical sciences, 2020 - cell.com
During interphase, filamentous actin, microtubules, and intermediate filaments regulate cell
shape, motility, transport, and interactions with the environment. These activities rely on …

Exosome-integrated titanium oxide nanotubes for targeted bone regeneration

F Wei, M Li, R Crawford, Y Zhou, Y Xiao - Acta biomaterialia, 2019 - Elsevier
Exosomes are extracellular nanovesicles that play an important role in cellular
communication. The modulatory effects of bone morphogenetic protein 2 (BMP2) on …

TAK1 is an essential kinase for STING trafficking

M Ma, Y Dang, B Chang, F Wang, J Xu, L Chen, H Su… - Molecular Cell, 2023 - cell.com
The translocation of stimulator of interferon genes (STING) from the endoplasmic reticulum
(ER) to the ER–Golgi intermediate compartment (ERGIC) enables its activation. However …

Tubulin post-translational modifications: the elusive roles of acetylation

B Carmona, HS Marinho, CL Matos, S Nolasco… - Biology, 2023 - mdpi.com
Simple Summary Microtubules (MTs) are dynamic structures that compose part of the cell
cytoskeleton. They play important roles in various cellular functions, such as intracellular …

Multifaceted roles of TAK1 signaling in cancer

H Mukhopadhyay, NY Lee - Oncogene, 2020 - nature.com
Context-specific signaling is a prevalent theme in cancer biology wherein individual
molecules and pathways can have multiple or even opposite effects depending on the tumor …

Immunoregulatory role of exosomes derived from differentiating mesenchymal stromal cells on inflammation and osteogenesis

F Wei, Z Li, R Crawford, Y Xiao… - Journal of tissue …, 2019 - Wiley Online Library
Bone marrow‐derived mesenchymal stem/stromal cells (BMSCs) can differentiate into bone‐
forming osteoblasts, playing a crucial role in bone regeneration. Exosomes are naturally cell …

[HTML][HTML] Direct and indirect effects of tubulin post-translational modifications on microtubule stability: Insights and regulations

J Bär, Y Popp, M Bucher, M Mikhaylova - Biochimica et Biophysica Acta …, 2022 - Elsevier
Microtubules (MTs) mediate various cellular functions such as structural support,
chromosome segregation, and intracellular transport. To achieve this, the pivotal properties …

PI3K/AKT signaling tips the balance of cytoskeletal forces for cancer progression

S Deng, HC Leong, A Datta, V Gopal, AP Kumar… - Cancers, 2022 - mdpi.com
Simple Summary The PI3K/AKT signaling pathway plays critical roles in regulating a series
of cellular changes to promote tumor development and progression. The cytoskeletal …

Insulin induces microtubule stabilization and regulates the microtubule plus-end tracking protein network in adipocytes*[S]

SS Parker, J Krantz, EA Kwak, NK Barker… - Molecular & Cellular …, 2019 - ASBMB
Insulin-stimulated glucose uptake is known to involve microtubules, although the function of
microtubules and the microtubule-regulating proteins involved in insulin action are poorly …