The myriad roles of cyclic AMP in microbial pathogens: from signal to sword

KA McDonough, A Rodriguez - Nature Reviews Microbiology, 2012 - nature.com
All organisms must sense and respond to their external environments, and this signal
transduction often involves second messengers such as cyclic nucleotides. One such …

Phage-bacterial interactions in the evolution of toxigenic Vibrio cholerae

SM Faruque, JJ Mekalanos - Virulence, 2012 - Taylor & Francis
Understanding the genetic and ecological factors which support the emergence of new
clones of pathogenic bacteria is vital to develop preventive measures. Vibrio cholerae the …

Phase Variable O Antigen Biosynthetic Genes Control Expression of the Major Protective Antigen and Bacteriophage Receptor in Vibrio cholerae O1

KD Seed, SM Faruque, JJ Mekalanos, SB Calderwood… - 2012 - journals.plos.org
The Vibrio cholerae lipopolysaccharide O1 antigen is a major target of bacteriophages and
the human immune system and is of critical importance for vaccine design. We used an O1 …

Quorum Regulated Resistance of Vibrio cholerae against Environmental Bacteriophages

MM Hoque, IB Naser, SMN Bari, J Zhu, JJ Mekalanos… - Scientific reports, 2016 - nature.com
Predation by bacteriophages can significantly influence the population structure of bacterial
communities. Vibrio cholerae the causative agent of cholera epidemics interacts with …

Classifying the unclassified: a phage classification method

CM Chibani, A Farr, S Klama, S Dietrich, H Liesegang - Viruses, 2019 - mdpi.com
This work reports the method ClassiPhage to classify phage genomes using sequence
derived taxonomic features. ClassiPhage uses a set of phage specific Hidden Markov …

Chitin colonization, chitin degradation and chitin‐induced natural competence of Vibrio cholerae are subject to catabolite repression

M Blokesch - Environmental microbiology, 2012 - Wiley Online Library
Although Vibrio cholerae is a human pathogen its primary habitat are aquatic environments.
In this environment, V. cholerae takes advantage of the abundance of zooplankton, whose …

[HTML][HTML] Small RNAs direct attack and defense mechanisms in a quorum sensing phage and its host

M Sprenger, M Siemers, S Krautwurst, K Papenfort - Cell Host & Microbe, 2024 - cell.com
Many, if not all, bacteria use quorum sensing (QS) to control collective behaviors, and more
recently, QS has also been discovered in bacteriophages (phages). Phages can produce …

A fructose/H+ symporter controlled by a LacI-type regulator promotes survival of pandemic Vibrio cholerae in seawater

Y Liu, B Liu, T Xu, Q Wang, W Li, J Wu, X Zheng… - Nature …, 2021 - nature.com
The bacterium Vibrio cholerae can colonize the human intestine and cause cholera, but
spends much of its life cycle in seawater. The pathogen must adapt to substantial …

On the interactions between virulent bacteriophages and bacteria in the gut

D Maura, L Debarbieux - Bacteriophage, 2012 - Taylor & Francis
Full article: On the interactions between virulent bacteriophages and bacteria in the gut Skip
to Main Content Taylor and Francis Online homepage Taylor and Francis Online homepage …

Rethinking the roles of CRP, cAMP, and sugar-mediated global regulation in the Vibrionaceae

DM Colton, EV Stabb - Current genetics, 2016 - Springer
Many proteobacteria modulate a suite of catabolic genes using the second messenger cyclic
3′, 5′-AMP (cAMP) and the cAMP receptor protein (CRP). Together, the cAMP-CRP …