Plant flavonoids: Classification, distribution, biosynthesis, and antioxidant activity

N Shen, T Wang, Q Gan, S Liu, L Wang, B Jin - Food chemistry, 2022 - Elsevier
Flavonoids are a group of natural polyphenol substances abundant in vegetables, fruits,
grains, and tea. As plant secondary metabolites, flavonoids play essential roles in many …

Molecular mechanisms for biosynthesis and assembly of nutritionally important very long chain polyunsaturated fatty acids in microorganisms

X Qiu, X Xie, D Meesapyodsuk - Progress in Lipid Research, 2020 - Elsevier
Very long chain polyunsaturated fatty acids (VLCPUFAs) such as docosahexaenoic acid
(DHA, 22: 6n-3), arachidonic acid (ARA, 20: 4n-6) and eicosapentaenoic acid (EPA, 20: 5 …

[HTML][HTML] Multi-omics view of recombinant Yarrowia lipolytica: Enhanced ketogenic amino acid catabolism increases polyketide-synthase-driven docosahexaenoic …

SJ Gasovic, D Dietrich, L Gläser, P Cao… - Metabolic …, 2023 - Elsevier
DHA is a marine PUFA of commercial value, given its multiple health benefits. The
worldwide emerging shortage in DHA supply has increased interest in microbial cell …

Computationally Guided Enzymatic Studies on Schizochytrium-Sourced Malonyl-CoA:ACP Transacylase

G Chi, X Cao, Q Li, C Yao, F Lu, Y Liu… - Journal of Agricultural …, 2022 - ACS Publications
The malonyl-CoA: ACP transacylase (MAT) domain is responsible for the selection and
incorporation of malonyl building blocks in the biosynthesis of polyunsaturated fatty acids …

Light-Induced Flavonoid Biosynthesis in Sinopodophyllum hexandrum with High-Altitude Adaptation

Q Zhao, M Dong, M Li, L Jin, PW Paré - Plants, 2023 - mdpi.com
Sinopodophyllum hexandrum is a perennial alpine herb producing the anti-cancer
metabolite podophyllotoxin (PPT). Although the adaptation of S. hexandrum to high altitudes …

Progress of potential drugs targeted in lipid metabolism research

K Liang, JY Dai - Frontiers in Pharmacology, 2022 - frontiersin.org
Lipids are a class of complex hydrophobic molecules derived from fatty acids that not only
form the structural basis of biological membranes but also regulate metabolism and maintain …

Control mechanism for carbon‐chain length in polyunsaturated fatty‐acid synthases

S Hayashi, M Naka, K Ikeuchi, M Ohtsuka… - Angewandte …, 2019 - Wiley Online Library
Polyunsaturated fatty acids (PUFAs) such as docosahexaenoic acid (DHA) and
eicosapentaenoic acid (EPA) are essential fatty acids. PUFA synthases are composed of …

Transcriptional regulation mechanism of flavonoids biosynthesis gene during fruit development in astragalus membranaceus

P Hu, Suriguga, M Zhao, S Chen, X Wu, Q Wan - Frontiers in Genetics, 2022 - frontiersin.org
Astragalus membranaceus, as an important medicinal plant, are an excellent source of
flavonoids. Flavonoid compounds in A. membranaceus have been widely used in medicine …

Comparative Transcriptomic Analysis Uncovers Genes Responsible for the DHA Enhancement in the Mutant Aurantiochytrium sp.

L Liu, Z Hu, S Li, H Yang, S Li, C Lv, M Zaynab… - Microorganisms, 2020 - mdpi.com
Docosahexaenoic acid (DHA), an-3 long-chain polyunsaturated fatty acid, is critical for
physiological activities of the human body. Marine eukaryote Aurantiochytrium sp. is …

Control Mechanism for cis Double‐Bond Formation by Polyunsaturated Fatty‐Acid Synthases

S Hayashi, Y Satoh, Y Ogasawara… - Angewandte Chemie …, 2019 - Wiley Online Library
Polyunsaturated fatty acids (PUFAs) such as docosahexaenoic acid (DHA),
eicosapentaenoic acid (EPA), and arachidonic acid (ARA) are essential fatty acids for …