Alzheimer's disease is a neurological disorder that results in cognitive and behavioral
impairment. Conventional treatment strategies, such as acetylcholinesterase inhibitor drugs …

Nucleic acid-based bioactive substances have recently emerged as a new class of next-
generation therapeutics, but their development has been limited by their relatively weak …

The growing knowledge on the mechanisms of gene silencing and gene regulation by non-
coding RNAs (ncRNA), mainly small interfering RNA (siRNA) and microRNA (miRNA), is …

The E6 and E7 oncoproteins of high-risk types of human papillomavirus (HR-HPV) are
crucial for the development of cervical cancer (CC). Small interfering RNAs (siRNAs) are …

Several studies have demonstrated the ability of graphene oxide (GO) to efficiently adsorb
small-interfering RNA (siRNA) on its surface and to transport it into cells. However, studies …

Cervical cancer induced by human papillomavirus (HPV) is the fourth highest mortality
causing cancer in women despite the use of prophylactic vaccines. E6 targeting represents …

AIM: This study aimed to construct a kind of PEG-coated irinotecan cationic liposomes for
investigating its efficacy and mechanism of action in the treatment of breast cancer in …

Modified cyclodextrins (CDs) have shown great promise as non-viral gene and siRNA
delivery vectors in a range of in vitro and in vivo studies. In the current study, structural and …

Layered double hydroxides (LDHs) have interesting properties and structures that enable
them to carry nucleic acids, such as deoxyribonucleic acid (DNA). This study synthesized …

This study evaluated the effectiveness of local administration of cationic liposome‐delivered
myostatin‐targeting si RNA. Myostatin (Mst)‐si RNA and scrambled (scr)‐si RNA‐lipoplexes …