Chalcones are among the leading bioactive flavonoids with a therapeutic potential
implicated to an array of bioactivities investigated by a series of preclinical and clinical …

Leishmaniasis is a group of infectious neglected tropical diseases caused by more than 20
pathogenic species of Leishmania sp. Due to the limitations of the current treatments …

In tropical and subtropical regions of the world, leishmaniasis is endemic and causes a
range of clinical symptoms in people, from severe tegumentary forms (such as cutaneous …

Leishmaniases are endemic diseases in tropical and sub-tropical regions of the world and
are considered by the World Health Organization (WHO) to be among the six most important …

Leishmaniasis is a chronic disease caused by protozoa of the distinct Leishmania genus
transmitted by sandflies of the genus Phlebotomus (old world) and Lutzomyia (new world) …

Arginase catalyzes the hydrolysis of l-arginine into l-ornithine and urea, acting as a key
enzyme in the biosynthesis of polyamines. Leishmania growth and survival is dependent on …

Chalcones, either natural or synthetic, are known to exhibit various biological activities. The
present study aimed to evaluate the in vitro and in silico activities of some chalcone …

Vulvovaginal candidiasis (VVC) affects millions of women around the world every year.
Candida albicans is the most frequently isolated pathogen in women and its rapid ability to …

Objectives Periodontitis is a pathology resulting from complex interaction of microorganisms
in the dental biofilm with the host's immune system. Increased use of antibiotics associated …

To survive in a very competitive environment, marine macroalgae had to evolve defense
strategies, resulting in an enormous diversity of compounds from different metabolic …