G protein-coupled receptors (GPCRs) are seven transmembrane helical bundle proteins
(Figure 1) found on the surface of all cells. 1-3 They mediate cellular responses to a diverse …

G protein-coupled receptors (GPCRs) represent the largest and most physiologically
important integral membrane protein family, and these receptors respond to a wide variety of …

Temperature coefficients have been measured by 2D NMR methods forthe amide and CαH
proton chemical shifts in two globularproteins, bovine pancreatic trypsin inhibitor and hen …

The conformational properties of a 16 residue peptide, corresponding to the second β-
hairpin of the B1 domain of protein G, have been studied by nuclear magnetic resonance …

Abstract Endothelin, a 21-amino-acid peptide, participates in various physiological
processes, such as regulation of vascular tone, humoral homeostasis, neural crest cell …

A detailed analysis of backbone amide NH chemical shift temperature gradients (Δδ/Δ T
values) for proteins and highly cross-linked peptides reveals that hydrogen-bonded …

Computation of the Fock matrix is currently the limiting factor in the application of Hartree-
Fock and hybrid Hartree-Fock/density functional theories to larger systems. Computation of …

In addition to involvement in vascular endothelium-smooth muscle communication, the
secretion of and receptors for, endothelins are widely distibuted. Two cloned receptor …

The methodology of regioselective cysteine pairings in synthetic multiple‐cystine peptides
has progressed in the past years to an efficiency that allows for at least three specific inter …

The solution structure of the isolated fragments 1–20 (β‐hairpin), 21–40 (α‐helix) and 41–56
(β‐hairpin), corresponding to all the secondary structure elements of the protein G B1 …