Uric acid is the final product of purine metabolism in humans. The final two reactions of its
production catalyzing the conversion of hypoxanthine to xanthine and the latter to uric acid …

Reactive oxygen species (ROS) were viewed for a long time as unavoidable by-products of
normal cell catabolism. This view has recently changed and it is now apparent that ROS …

Oxidative stress is an important factor in many pathological conditions such as inflammation,
cancer, ageing and organ response to ischemia‐reperfusion. Humans have developed a …

Metals are necessary for the normal functioning of cells and the survival of organisms.
However, exposure to higher than the physiological levels of several metals may lead to …

Aspects of the molecular mechanism (s) of hydrogen peroxide-induced DNA damage and
cell death were studied in the present investigation. Jurkat T-cells in culture were exposed …

Reactive oxygen species (ROS) and reactive nitrogen species (RNS) are created in normal
hepatocytes and are critical for normal physiologic processes, including oxidative …

Oxidative Stress in Hepatic Ischemia-Reperfusion Injury: The Role of Antioxidants and Iron
Chelating Compounds Page 1 Current Pharmaceutical Design, 2006, 12, 2875-2890 2875 …

Jurkat cells in culture were exposed to oxidative stress in the form of continuously generated
hydrogen peroxide, obtained by the addition of glucose oxidase to the medium. This …

Epidemiological studies continue to support the premise that diets rich in fruits and
vegetables may offer protection against cancer of various anatomic sites. This correlation is …

In search for compounds, able to protect nuclear DNA in cells exposed to oxidative stress,
extracts from olive leaves, olive fruits, olive oil and olive mill waste water were tested by …