Biological organisms learn from interactions with their environment throughout their lifetime.
For artificial systems to successfully act and adapt in the real world, it is desirable to similarly …

The locus coeruleus (LC), or 'blue spot', is a small nucleus located deep in the brainstem
that provides the far-reaching noradrenergic neurotransmitter system of the brain. This …

Simple Summary Over the past few decades, advances in electroencephalography (EEG)
recordings and brain stimulation has permitted an unprecedented view of how specific brain …

A key question in decision-making is how humans arbitrate between competing learning
and memory systems to maximize reward. We address this question by probing the balance …

Expressions such as 'sleep on it'refer to the resolution of distressing experiences across a
night of sound sleep. Sleep is an active state during which the brain reorganizes the …

Memories are stored in the brain as cellular ensembles activated during learning and
reactivated during retrieval. Using the Tet-tag system in mice, we label dorsal dentate gyrus …

People use information flexibly. They often combine multiple sources of relevant information
over time in order to inform decisions with little or no interference from intervening irrelevant …

The noradrenergic locus coeruleus (LC) is among the earliest sites of tau and α-synuclein
pathology in Alzheimer's disease (AD) and Parkinson's disease (PD), respectively. The …

Here, we review the basis of contextual memory at a conceptual and cellular level. We begin
with an overview of the philosophical foundations of traversing space, followed by theories …

The locus coeruleus (LC) plays a central role in regulating human cognition, arousal, and
autonomic states. Efforts to characterize the LC's function in humans using functional …