Hijacking of embryonic programs by neural crest-derived neuroblastoma: from physiological migration to metastatic dissemination

C Delloye-Bourgeois, V Castellani - Frontiers in molecular …, 2019 - frontiersin.org
In the developing organism, complex molecular programs orchestrate the generation of cells
in adequate numbers, drive them to migrate along the correct pathways towards appropriate …

Draxin acts as a molecular rheostat of canonical Wnt signaling to control cranial neural crest EMT

EJ Hutchins, ME Bronner - Journal of Cell Biology, 2018 - rupress.org
Neural crest cells undergo a spatiotemporally regulated epithelial-to-mesenchymal
transition (EMT) that proceeds head to tailward to exit from the neural tube. In this study, we …

From neural tube to spinal cord: The dynamic journey of the dorsal neuroepithelium

S Ventriglia, C Kalcheim - Developmental Biology, 2024 - Elsevier
In a developing embryo, formation of tissues and organs is remarkably precise in both time
and space. Through cell-cell interactions, neighboring progenitors coordinate their activities …

Identification of SNPs and candidate genes associated with early growth in orange-spotted grouper (Epinephelus coioides) by a genome-wide association study

CH Ai, ZX Zhu, DD Huang, G Yang, T De Liu, Y Bai… - Aquaculture, 2023 - Elsevier
Orange-spotted grouper, Epinephelus coioides is one of the most economically important
marine fish in the South China Sea. Exploring of the genetic basis controlling for the growth …

Loss of PPARγ in endothelial cells leads to impaired angiogenesis

S Vattulainen-Collanus, O Akinrinade… - Journal of cell …, 2016 - journals.biologists.com
Tie2-promoter-mediated loss of peroxisome proliferator-activated receptor gamma (PPARγ,
also known as PPARG) in mice leads to osteopetrosis and pulmonary arterial hypertension …

Proteoglycan (keratan sulfate) barrier in developing human forebrain isolates cortical epileptic networks from deep heterotopia, insulates axonal fascicles, and …

HB Sarnat - Journal of Neuropathology & Experimental …, 2019 - academic.oup.com
Axons from deep heterotopia do not extend through U-fibers, except transmantle dysplasias.
Keratan sulfate (KS) in fetal spinal cord/brainstem median septum selectively repels …

A chemotactic model of trunk neural crest cell migration

L Dyson, A Holmes, A Li, PM Kulesa - genesis, 2018 - Wiley Online Library
Trunk neural crest cells follow a common ventral migratory pathway but are distributed into
two distinct locations to form discrete sympathetic and dorsal root ganglia along the …

Draxin regulates hippocampal neurogenesis in the postnatal dentate gyrus by inhibiting DCC-induced apoptosis

H Tawarayama, H Yamada, R Amin… - Scientific Reports, 2018 - nature.com
Hippocampal neurogenesis in the dentate gyrus (DG) is controlled by diffusible molecules
that modulate neurogenic processes, including cell proliferation, differentiation and survival …

A potential inhibitory function of draxin in regulating mouse trunk neural crest migration

S Zhang, Y Su, J Gao, C Zhang, H Tanaka - In Vitro Cellular & …, 2017 - Springer
Draxin is a repulsive axon guidance protein that plays important roles in the formation of
three commissures in the central nervous system and dorsal interneuron 3 (dI3) in the chick …

Transcriptomic identification of draxin-responsive targets during cranial neural crest EMT

EJ Hutchins, ML Piacentino, ME Bronner - Frontiers in Physiology, 2021 - frontiersin.org
Canonical Wnt signaling plays an essential role in proper craniofacial morphogenesis, at
least partially due to regulation of various aspects of cranial neural crest development. In an …