Specialized pro-resolving mediator network: an update on production and actions

N Chiang, CN Serhan - Essays in Biochemistry, 2020 - portlandpress.com
Today, persistent and uncontrolled inflammation is appreciated to play a pivotal role in many
diseases, such as cardiovascular diseases, neurodegenerative diseases, metabolic …

E-series resolvin metabolome, biosynthesis and critical role of stereochemistry of specialized pro-resolving mediators (SPMs) in inflammation-resolution: Preparing …

CN Serhan, S Libreros, R Nshimiyimana - Seminars in immunology, 2022 - Elsevier
The COVID-19 pandemic has raised international awareness of the importance of rigorous
scientific evidence and the havoc caused by uncontrolled excessive inflammation. Here we …

Cold‐stored platelets have better preserved contractile function in comparison with room temperature‐stored platelets over 21 days

PM Nair, MA Meledeo, AR Wells, X Wu, JA Bynum… - …, 2021 - Wiley Online Library
Although it is well established that transfusion of platelets in cases of severe bleeding
reduces mortality, the availability of platelets is hampered by harsh restrictions on shelf life …

Associations of gut microbiota and fatty metabolism with immune thrombocytopenia

X Yu, Q Zheng, Y He, D Yu, G Chang, C Chen… - Frontiers in …, 2022 - frontiersin.org
Objective To determine whether gut microbiota, fatty metabolism and cytokines were
associated with immune thrombocytopenia (ITP). Methods In total, 29 preliminarily …

The missing pieces to the cold-stored platelet puzzle

H Zhao, DV Devine - International Journal of Molecular Sciences, 2022 - mdpi.com
Cold-stored platelets are making a comeback. They were abandoned in the late 1960s in
favor of room-temperature stored platelets due to the need for longer post-transfusion …

The anti-aggregative potential of resolvin E1 on human platelets

P Szymańska, B Luzak, K Miłowska, J Golański - Molecules, 2023 - mdpi.com
Resolvin E1 is a metabolite of eicosapentaenoic acid (EPA) which is one of the omega-3
polyunsaturated fatty acids (omega-3 PUFAs). The antiplatelet properties of omega-3 PUFAs …

Maresin: Macrophage Mediator for Resolving Inflammation and Bridging Tissue Regeneration—A System-Based Preclinical Systematic Review

WC Liu, YH Yang, YC Wang, WM Chang… - International journal of …, 2023 - mdpi.com
Maresins are lipid mediators derived from omega-3 fatty acids with anti-inflammatory and
pro-resolving properties, capable of promoting tissue regeneration and potentially serving …

Gut microbiome composition and dysbiosis in immune thrombocytopenia: A review of literature

N Saki, H Hadi, B Keikhaei, A Mirzaei, D Purrahman - Blood Reviews, 2024 - Elsevier
Immune thrombocytopenia (ITP) is an autoimmune bleeding disorder characterized by
excessive reticuloendothelial platelet destruction and inadequate compensatory platelet …

Lipid mediators in neutrophil biology: inflammation, resolution and beyond

A Ghodsi, A Hidalgo, S Libreros - Current Opinion in Hematology, 2024 - journals.lww.com
SPMs play a pivotal role in mitigating excessive neutrophil infiltration and hyperactivity
within pathological milieus, notably in conditions such as sepsis, cardiovascular disease …

The evaluation of cold-stored platelets

HQ Zhao - 2022 - open.library.ubc.ca
Platelets are an integral part of transfusion medicine. In Canada, over 80% of the platelet
units for transfusion are produced via the buffy coat method from whole blood and stored in …