Advances in histone demethylase KDM4 as cancer therapeutic targets

DH Lee, GW Kim, YH Jeon, J Yoo, SW Lee… - The FASEB …, 2020 - Wiley Online Library
Abstract The KDM4 subfamily H3K9 histone demethylases are epigenetic regulators that
control chromatin structure and gene expression by demethylating histone H3K9, H3K36 …

Diabetes mellitus is a chronic disease that can benefit from therapy with induced pluripotent stem cells

F Arroyave, D Montaño, F Lizcano - International Journal of Molecular …, 2020 - mdpi.com
Diabetes mellitus (DM) is one of the main causes of morbidity and mortality, with an
increasing incidence worldwide. The impact of DM on public health in developing countries …

Expression patterns of novel circular RNAs in chicken cells after avian leukosis virus subgroup J infection

Y Zhang, L Wang, L Qiu, R Pan, H Bai, Y Jiang, Z Wang… - Gene, 2019 - Elsevier
Avian leukosis virus subgroup J (ALV-J) is an oncogenic retrovirus that causes severe
economic losses to the poultry industry worldwide. Circular RNAs (circRNAs) are a class of …

Alterations of histone modifications in cancer

MM Saber-Ayad, WSH Ramadan… - Epigenetics in Human …, 2024 - Elsevier
Histones are the key protein components of the nucleosome, the basic unit of chromatin.
Histones undergo several posttranslational modifications (PTMs) that, together with DNA …

KDM4C Promotes Proliferation and Migration of Multiple Myeloma Cells by Up-Regulating JAG1 Gene Expression

D Yu, M Hu, Q Tian - Journal of Hard Tissue Biology, 2021 - jstage.jst.go.jp
Multiple myeloma is a frequent hematological malignancy. Although progress has been
made in therapeutic strategies, the prognosis of multiple myeloma is far from satisfactory …