Soft tissue sarcomas (STSs) are an uncommon group of solid tumors that can arise
throughout the human lifespan. Despite their commonality as non-bony cancers that develop …

Parasites have attained a life-long stigma of being detrimental organisms with deleterious
outcomes. Yet, recently, a creditable twist was verified that can dramatically change our …

Exosomes are a type of extracellular vesicles containing mRNA, miRNA, and proteins of
origin cells, which can control the characteristics of other cells or surroundings. Despite …

Fibrosarcoma, a malignant mesenchymal tumor, is characterized by aggressive
invasiveness and a high recurrence rate, leading to poor prognosis. Anthracycline drugs …

Background Cancer‐associated cachexia (CAC) is a wasting syndrome drastically reducing
efficacy of chemotherapy and life expectancy of patients. CAC affects up to 80% of cancer …

Ferroptosis is a recently discovered programmed cell death pathway initiated by reactive
oxygen species (ROS). Cancer cells can escape ferroptosis, and strategies to promote …

The efficacy of fluorescence-guided surgery in facilitating the real-time delineation of
tumours depends on the optical contrast of tumour tissue over healthy tissue. Here we show …

Local administration of drugs at tumor sites over an extended period of time shows potential
as a promising approach for cancer treatment. In the present study, the temperature-induced …

Background: We have previously shown that alendronate, an amino-bisphosphonate, when
reformulated in liposomes, can significantly enhance the efficacy of cytotoxic …

Sarcomas are a heterogeneous group of rare cancers that originate in soft tissues or bones.
Their complexity and tendency for metastases make treatment challenging, highlighting the …