DNA-mediated homogeneous binding assays for nucleic acids and proteins
The detection of nucleic acids and proteins is fundamental for studying their functions and
for the development of molecular diagnostics. These molecules carry out most biological …
for the development of molecular diagnostics. These molecules carry out most biological …
Aptamers facilitating amplified detection of biomolecules
Since they were first reported by two independent research groups 1, 2 in 1990, aptamers
have been widely used in analytical detection, separation, diagnostics, imaging, and …
have been widely used in analytical detection, separation, diagnostics, imaging, and …
Electrospun nanofibers for cancer diagnosis and therapy
The advent of nanotechnology has provided unprecedented opportunities for nanomedicine.
Electrospun nanofibers have some astounding features such as high loading capacity …
Electrospun nanofibers have some astounding features such as high loading capacity …
Quantitation of femtomolar protein levels via direct readout with the electrochemical proximity assay
We have developed a separation-free, electrochemical assay format with direct readout that
is amenable to highly sensitive and selective quantitation of a wide variety of target proteins …
is amenable to highly sensitive and selective quantitation of a wide variety of target proteins …
Immunoreaction-triggered DNA assembly for one-step sensitive ratiometric electrochemical biosensing of protein biomarker
K Ren, J Wu, F Yan, Y Zhang, H Ju - Biosensors and Bioelectronics, 2015 - Elsevier
A sensitive ratiometric electrochemical readout was designed with an immunoreaction-
triggered DNA assembly for one-step, fast and flexible assay of protein biomarker. The …
triggered DNA assembly for one-step, fast and flexible assay of protein biomarker. The …
A reusable electrochemical proximity assay for highly selective, real-time protein quantitation in biological matrices
Rapid and specific quantitation of a variety of proteins over a wide concentration range is
highly desirable for biosensing at the point-of-care, in clinical laboratories, and in research …
highly desirable for biosensing at the point-of-care, in clinical laboratories, and in research …
Proximity hybridization-regulated immunoassay for cell surface protein and protein-overexpressing cancer cells via electrochemiluminescence
X Wang, H Gao, H Qi, Q Gao, C Zhang - Analytical chemistry, 2018 - ACS Publications
A simple electrochemiluminescence (ECL) immunoassay based on a proximity hybridization-
regulated strategy was developed for highly sensitive and specific detection of cell surface …
regulated strategy was developed for highly sensitive and specific detection of cell surface …
Enhanced photoelectrochemical proximity assay for highly selective protein detection in biological matrixes
G Wen, H Ju - Analytical chemistry, 2016 - ACS Publications
This work proposes the first photoelectrochemical proximity assay (PECPA) method via the
sensitization of CdTe quantum dots (QDs) on photoelectrochemical response of …
sensitization of CdTe quantum dots (QDs) on photoelectrochemical response of …
Sensitivity and specificity: twin goals of proteomics assays. Can they be combined?
R Wilson - Expert review of proteomics, 2013 - Taylor & Francis
A major ambition of proteomics is the provision of assays that can diagnose disease and
monitor therapies. These assays are required to be sensitive and specific for individual …
monitor therapies. These assays are required to be sensitive and specific for individual …
Nucleic-acid driven cooperative bioassays using probe proximity or split-probe techniques
AB Bezerra, ASN Kurian, CJ Easley - Analytical chemistry, 2020 - ACS Publications
Among the many advancements in biosensing over the last few decades, a number of
powerful and practically useful assays have been devised by mimicking binding and …
powerful and practically useful assays have been devised by mimicking binding and …