Brain waves resonate from the generators of electrical current and propagate across brain
regions with oscillation frequencies ranging from 0.05 to 500 Hz. The commonly observed …

Over the past forty years, animal models of focal cerebral ischaemia have allowed us to
identify the critical cerebral blood flow thresholds responsible for irreversible cell death …

Electroencephalography (EEG) has a long history in clinical evaluations of cerebrovascular
disease. Distinct EEG abnormalities, such as increased slow delta activity, voltage …

Background After ischemia of the CNS, extracellular adenosine 5′-triphosphate (ATP) can
reach high concentrations due to cell damage and subsequent increase of membrane …

Stroke is the second-leading cause of death globally and the leading cause of disability in
adults. Medical complications after stroke, especially infections such as pneumonia, are the …

Cerebrovascular diseases are one of the most common causes of epilepsy in adults, and the
incidence of stroke-induced epileptogenesis is increasing as the population ages. The …

Our objective is to develop a new therapy for the treatment of stroke. Currently, the only
effective therapy for acute ischemic stroke is the thrombolytic agent recombinant tissue …

Transient focal ischemia produced by local infusion of endothelin-1 (ET1) in the territory of
the middle cerebral artery has been proposed as a potentially useful model for the screening …

Animal models are useful tools for better understanding the mechanisms underlying
neurological deterioration after an ischemic insult as well as subsequent evolution of …

The purpose of this study was to characterize the magnitude and duration of cerebral blood
flow (CBF) reduction in the somatosensory cortical region in a rat model of middle cerebral …