Advances in molecular pharmacology and an improved understanding of the mechanism of
most diseases have created the need to specifically target the cells involved in the initiation …

In situ gelling formulations are drug delivery systems which typically exist in a liquid form at
room temperature and change into gel state after application to the body in response to …

In situ gelling devices, as they enter the body, are dosage forms in the shape of the sol but
turn into gel types under physiological circumstances. Transition from sol to gel is contingent …

The current review on in situ gelling systems becomes one of the most popular and
prominent. It had a tremendous potential advantage of delivery systems due to many …

Novel in situ gelling liquid formulations incorporating garcinia extract were developed to
achieve prolonged delivery of hydroxycitric acid (HCA), an active compound displaying anti …

This study delved on development of curcumin loaded Nanostructured Lipid carrier (NLC)
incorporated into gastro-retentive oral in-situ gel for specifically designed to the stomach …

Background: The in-situ solutions, which float in the gastrointestinal region after gelation, is
suited for long-term drug release. In this study, natural and synthetic polymers were used to …

This study investigated polymeric blends of cellulose derivatives and poloxamer 407 as
thermoresponsive and bioadhesive systems for drug delivery, with focus on the topical …

Celecoxib (CXB) is a COX‐2‐selective nonsteroidal anti‐inflammatory drug used to control
pain and various inflammatory conditions. CXB has limited oral bioavailability and a slow …

Disadvantages* In-situ gel framing systems are more susceptible to stability problems
because of chemical or microbiological degradation.* Change in pH may prompt to …