Present and future of bronchopulmonary dysplasia

L Bonadies, P Zaramella, A Porzionato… - Journal of clinical …, 2020 - mdpi.com
Bronchopulmonary dysplasia (BPD) is the most common respiratory disorder among infants
born extremely preterm. The pathogenesis of BPD involves multiple prenatal and postnatal …

Prediction of preterm birth: maternal characteristics, ultrasound markers, and biomarkers: an updated overview

ZA Oskovi Kaplan, AS Ozgu-Erdinc - Journal of pregnancy, 2018 - Wiley Online Library
There is not a single or combined screening method for preterm birth with high sensitivity
which will truly identify the women at risk for preterm birth while also with high specificity to …

Lung ultrasound to monitor extremely preterm infants and predict bronchopulmonary dysplasia. A multicenter longitudinal cohort study

B Loi, G Vigo, E Baraldi, F Raimondi… - American journal of …, 2021 - atsjournals.org
Rationale: Lung ultrasound is useful in critically ill patients with acute respiratory failure.
Given its characteristics, it could also be useful in extremely preterm infants with evolving …

[HTML][HTML] Toward a new taxonomy of obstetrical disease: improved performance of maternal blood biomarkers for the great obstetrical syndromes when classified …

R Romero, E Jung, T Chaiworapongsa, O Erez… - American journal of …, 2022 - Elsevier
Background The major challenge for obstetrics is the prediction and prevention of the great
obstetrical syndromes. We propose that defining obstetrical diseases by the combination of …

Recent advances in our understanding of the mechanisms of late lung development and bronchopulmonary dysplasia

DE Surate Solaligue… - … of Physiology-Lung …, 2017 - journals.physiology.org
The objective of lung development is to generate an organ of gas exchange that provides
both a thin gas diffusion barrier and a large gas diffusion surface area, which concomitantly …

Amniotic fluid exosome proteomic profile exhibits unique pathways of term and preterm labor

CL Dixon, S Sheller-Miller, GR Saade… - …, 2018 - academic.oup.com
Our objective was to determine the amniotic fluid–derived exosomal proteomic profile in
patients who had spontaneous preterm birth (PTB) or preterm premature rupture of …

Intratracheal administration of clinical-grade mesenchymal stem cell-derived extracellular vesicles reduces lung injury in a rat model of bronchopulmonary dysplasia

A Porzionato, P Zaramella, A Dedja… - … of Physiology-Lung …, 2019 - journals.physiology.org
Mesenchymal stem cells (MSCs) prevent the onset of bronchopulmonary dysplasia (BPD) in
animal models, an effect that seems to be mediated by their secreted extracellular vesicles …

[HTML][HTML] Emerging role of metabolic reprogramming in hyperoxia-associated neonatal diseases

T Sun, H Yu, D Li, H Zhang, J Fu - Redox Biology, 2023 - Elsevier
Oxygen therapy is common during the neonatal period to improve survival, but it can
increase the risk of oxygen toxicity. Hyperoxia can damage multiple organs and systems in …

Phenotypes of bronchopulmonary dysplasia

SH Wang, PN Tsao - International Journal of Molecular Sciences, 2020 - mdpi.com
Bronchopulmonary dysplasia (BPD) is the most common chronic morbidity in preterm
infants. In the absence of effective interventions, BPD is currently a major therapeutic …

Preterm birth is associated with xenobiotics and predicted by the vaginal metabolome

WF Kindschuh, F Baldini, MC Liu, J Liao… - Nature …, 2023 - nature.com
Spontaneous preterm birth (sPTB) is a leading cause of maternal and neonatal morbidity
and mortality, yet its prevention and early risk stratification are limited. Previous …