[HTML][HTML] The Discovery of inhibitors of the SARS-CoV-2 S protein through computational drug repurposing
AI Avilés-Alía, J Zulaica, JJ Perez… - Computers in biology …, 2024 - Elsevier
SARS-CoV-2 must bind its principal receptor, ACE2, on the target cell to initiate infection.
This interaction is largely driven by the receptor binding domain (RBD) of the viral Spike (S) …
This interaction is largely driven by the receptor binding domain (RBD) of the viral Spike (S) …
Assessment of the bound conformation of bombesin to the BB1 and BB2 receptors
Bombesin is an endogenous peptide involved in a wide spectrum of physiological activities
ranging from satiety, control of circadian rhythm and thermoregulation in the central nervous …
ranging from satiety, control of circadian rhythm and thermoregulation in the central nervous …
Shedding Light on Dark Chemical Matter: The Discovery of a SARS-CoV-2 Mpro Main Protease Inhibitor through Intensive Virtual Screening and In Vitro Evaluation
MN Peralta-Moreno, Y Mena, D Ortega-Alarcon… - International Journal of …, 2024 - mdpi.com
The development of specific antiviral therapies targeting SARS-CoV-2 remains fundamental
because of the continued high incidence of COVID-19 and limited accessibility to antivirals …
because of the continued high incidence of COVID-19 and limited accessibility to antivirals …
On the importance for drug discovery of a transnational Latin American database of natural compound structures
TM Thomson - Frontiers in Pharmacology, 2023 - frontiersin.org
Drug development is a complex, risky, expensive and time-consuming process that requires
the accurate execution of multiple stages, from identification and selection of collections of …
the accurate execution of multiple stages, from identification and selection of collections of …
Assessment of the bound conformation of Bombesin to the BB1 and BB2 Receptors
Bombesin is an endogenous peptide involved in a wide spectrum of physiological activities
ranging from satiety, control of circadian rhythm and thermoregulation in the central nervous …
ranging from satiety, control of circadian rhythm and thermoregulation in the central nervous …