Cell therapies offer a tailorable, personalized treatment for use in tissue engineering to
address defects arising from trauma, inefficient wound repair, or congenital malformation …

Chronic, non-healing, dermal wounds form a worldwide medical problem with limited and
inadequate treatment options and high societal burden and costs. With the advent of …

Integrin is a widely distributed adhesion molecule on cell membrane surface, which plays a
role in transferring mechanical properties signals of the extracellular matrix into cells during …

Background The ability of mesenchymal stem cells (MSCs) to migrate to the desired tissues
or lesions is crucial for stem cell-based regenerative medicine and tissue engineering …

Recent advances in scaffold-free three-dimensional (3D) culture methods have significantly
enhanced the potential of stem cell-based therapies in regenerative medicine. This cutting …

Background Angiogenesis is of utmost importance for tissue regeneration and repair.
Human dental pulp stromal cells (hDPSCs) possess angiogenic potential, as they secrete …

Simple Summary In adult mammals, including humans, new blood vessels are formed
mostly via a process named sprouting angiogenesis. In physiological conditions …

Active self-encapsulation (ASE) is a recently developed post-loading method based on
absorption of (positively charged) proteins in microporous PLGA microspheres loaded with …

Highlights•Therapeutic angiogenesis aims at stimulating new blood vessel formation.•In vitro
models for assessing the angiogenic potential of a product are revised.•Practical examples …

A functional vascular system is a prerequisite for bone repair as disturbed angiogenesis
often causes non-union. Paracrine factors released from human bone marrow derived …