Blood contains microparticles (MPs) derived from a variety of cell types, including platelets,
monocytes, and endothelial cells. In addition, tumors release MPs into the circulation. MPs …

Platelet adhesion, activation and aggregation on the exposed subendothelial extracellular
matrix (ECM) are essential for haemostasis, but may also lead to occlusion of diseased …

The aim of the present study was to compare different diets used to induce obesity in a head-
to-head manner with a focus on insulin resistance and vascular dysfunction. Male C57BL/6J …

Systemic delivery of mRNA-based therapeutics remains a challenging issue for preclinical
and clinical studies. Here, we describe new lipid-like nanoparticles (TT-LLNs) developed …

The effects of rutin and rutin glycoside with different solubility were compared on antioxidant
activity and anti-inflammatory effects in vitro and the effects on platelet aggregation and …

Clinical observations and accumulating laboratory evidence support a complex interplay
between coagulation, inflammation, innate immunity and fibrinolysis in venous …

Deep vein thrombosis and pulmonary embolism are a significant health care concern,
representing a major source of mortality and morbidity. In order to understand the …

See also Brill A. A ride with ferric chloride. This issue, pp 776–8. Summary Background: The
FeCl 3‐induced vascular injury model is widely used to study thrombogenesis in vivo, but …

METHODS: Bleeding assay was performed in mice by tail tip amputation, immersing the tail
in saline at 37 C, continuously monitoring bleeding patterns and measuring bleeding …

Platelets play an essential role in hemostasis and atherothrombosis. Owing to their short
storage time, there is constant demand for this life-saving blood component. In this study, we …