Circadian rhythms and disorders of the timing of sleep
The daily alternation between sleep and wakefulness is one of the most dominant features
of our lives and is a manifestation of the intrinsic 24 h rhythmicity underlying almost every …
of our lives and is a manifestation of the intrinsic 24 h rhythmicity underlying almost every …
Novel approaches for assessing circadian rhythmicity in humans: a review
The temporal organization of molecular and physiological processes is driven by
environmental and behavioral cycles as well as by self-sustained molecular circadian …
environmental and behavioral cycles as well as by self-sustained molecular circadian …
State of the science and recommendations for using wearable technology in sleep and circadian research
Wearable sleep-tracking technology is of growing use in the sleep and circadian fields,
including for applications across other disciplines, inclusive of a variety of disease states …
including for applications across other disciplines, inclusive of a variety of disease states …
Predicting circadian misalignment with wearable technology: validation of wrist-worn actigraphy and photometry in night shift workers
Study Objectives A critical barrier to successful treatment of circadian misalignment in shift
workers is determining circadian phase in a clinical or field setting. Light and movement data …
workers is determining circadian phase in a clinical or field setting. Light and movement data …
Predicting circadian phase across populations: a comparison of mathematical models and wearable devices
From smart work scheduling to optimal drug timing, there is enormous potential in translating
circadian rhythms research results for precision medicine in the real world. However, the …
circadian rhythms research results for precision medicine in the real world. However, the …
A population-based gene expression signature of molecular clock phase from a single epidermal sample
Background For circadian medicine to influence health, such as when to take a drug or
undergo a procedure, a biomarker of molecular clock phase is required––one that is easily …
undergo a procedure, a biomarker of molecular clock phase is required––one that is easily …
The interindividual variability of sleep timing and circadian phase in humans is influenced by daytime and evening light conditions
Human cognitive functioning shows circadian variations throughout the day. However,
individuals largely differ in their timing during the day of when they are more capable of …
individuals largely differ in their timing during the day of when they are more capable of …
Computational approaches for individual circadian phase prediction in field settings
Abstract Knowledge of circadian phase is critical for timing interventions for circadian rhythm
disorders, medications, or predicting alertness. Current gold-standard measures of circadian …
disorders, medications, or predicting alertness. Current gold-standard measures of circadian …
The role of light sensitivity and intrinsic circadian period in predicting individual circadian timing
There is large interindividual variability in circadian timing, which is underestimated by
mathematical models of the circadian clock. Interindividual differences in timing have …
mathematical models of the circadian clock. Interindividual differences in timing have …
A real-time, personalized sleep intervention using mathematical modeling and wearable devices
The prevalence of artificial light exposure has enabled us to be active any time of the day or
night, leading to the need for high alertness outside of traditional daytime hours. To address …
night, leading to the need for high alertness outside of traditional daytime hours. To address …