Polyurethane elastomers have a combination of excellent mechanical, physical and
chemical properties along with exceptional biocompatibility. Therefore, these elastomeric …

Ophthalmic drugs used for the treatment of various ocular diseases are commonly
administered by eye drops. However, due to anatomical and physiological factors, there is a …

Hydrogels are extensively used in the biomedical field, as drug delivery systems, wound
dressings, contact lenses or as scaffolds for tissue engineering. Due to their polymeric …

Despite the beneficial properties and outstanding potential of hydrogels for biomedical
applications, several unmet challenges must be overcome, especially regarding to their …

The sustained and/or targeted delivery of hydrophilic drugs is an important field within drug
delivery, presenting unique challenges when compared to that of hydrophobic drugs. Yet …

Efficient ocular drug delivery that can overcome the challenges of topical application has
been largely pursued. Contact lenses (CLs) may act as light-transparent cornea/sclera …

Contact lenses (CLs) offer a wide variety of advantages as ocular drug-releasing platforms,
but the feasibility of medicated CL development is constrained by numerous scientific …

Therapeutic contact lenses for ocular drug delivery have received considerable interest as
they can potentially enhance ocular bioavailability, increase patient compliance, and reduce …

Thin and erodible polymeric films were developed as potential ocular drug delivery systems
to increase drug retention on the eye with the aim of improving bioavailability and achieving …

The purpose of this study is to extend drug release from ACUVUE Oasys® and ACUVUE
TruEye® silicone hydrogel contact lenses by incorporation of vitamin E in conjunction with a …