Tissue engineering (TE) aims to regenerate critical size defects, which cannot heal naturally,
by using highly porous matrices called TE scaffolds made of biocompatible and …

Surgical meshes have been employed in the management of a variety of pathological
conditions including hernia, pelvic floor dysfunctions, periodontal guided bone regeneration …

Wound healing involves a complex series of events where cell–cell and cell-extracellular
matrix (ECM) interactions play a key role. Wounding can be simple, such as the loss of the …

Vaginal meshes used in the treatment of stress urinary incontinence (SUI) and pelvic organ
prolapse (POP) have produced highly variable outcomes, causing life-changing …

Pelvic floor dysfunction (PFD) is a common gynecological problem that affects millions of
women. Current treatment strategies are to restore the normal anatomical structure by non …

Background: The reconstructive surgery of vaginal defects is highly demanding and
susceptible to complications, especially in larger defects requiring nonvaginal tissue grafts …

Background Polypropylene meshes cause severe complications in some patients. Materials
that are biomechanically compatible and can better integrate into host tissues are urgently …

A scaffold is a major requirement in tissue engineering which can mimic the targeted site of
an injury and can give support to the cells to adhere and proliferate by allowing the …

Pelvic organ prolapse is the herniation of surrounding tissue and organs into the vagina
and/or rectum and is a result of the weakening of pelvic floor muscles, connective tissue, and …

Aims Pelvic organ prolapse and stress urinary incontinence affect 40‐50% of
postmenopausal women worldwide. Polypropylene meshes have been extensively used for …